The planning and execution of a business strategy are important aspects of the strategic human resource management of a company. In previous studies, machine learning algorithms were used to determine the main factors correlating employees with company performance. In this study, we introduced a method based on machine-learning algorithms for the classification of company revenue. Both annual and integrated datasets were examined to evaluate the classification performance of the framework under both binary and multiclass conditions. The performance of the proposed method was validated using six evaluation metrics: accuracy, precision, recall, F1-score, receiver operating characteristic curve, and area under the curve. As the experimental results indicate, the XGBoost classifier displayed the best classification performance among the three algorithms (XGBoost classifier, stochastic gradient descent classifier, and logistic regression) used in this study. Moreover, we confirmed the important features of the trained XGBoost model in accordance with variables focusing on human resource management studies. These results demonstrate that the proposed framework has strength in terms of both classification and practical implementation. This study provides novel insights into the relationship between employees and the revenue levels of their employer.
Gene expression profiling technologies have been used in various applications such as cancer biology. The development of gene expression profiling has expanded the scope of target discovery in transcriptomic studies, and each technology produces data with distinct characteristics. In order to guarantee biologically meaningful findings using transcriptomic experiments, it is important to consider various experimental factors in a systematic way through statistical power analysis. In this paper, we review and discuss the power analysis for three types of gene expression profiling technologies from a practical standpoint, including bulk RNA-seq, single-cell RNA-seq, and high-throughput spatial transcriptomics. Specifically, we describe the existing power analysis tools for each research objective for each of the bulk RNA-seq and scRNA-seq experiments, along with recommendations. On the other hand, since there are no power analysis tools for high-throughput spatial transcriptomics at this point, we instead investigate the factors that can influence power analysis.
Since the emergence of the worldwide pandemic of COVID-19, relevant research has been published at a dazzling pace, which makes it hard to follow the research in this area without dedicated efforts. It is practically impossible to implement this task manually due to the high volume of the relevant literature. Text mining has been considered to be a powerful approach to address this challenge, especially the topic modeling, a well-known unsupervised method that aims to reveal latent topics from the literature. However, in spite of its potential utility, the results generated from this approach are often investigated manually. Hence, its application to the COVID-19 literature is not straightforward and expert knowledge is needed to make meaningful interpretations. In order to address these challenges, we propose a novel analytical framework for effective visualization and mining of topic modeling results. Here we assumed that topics constituting a paper can be positioned on an interaction map, which belongs to a high-dimensional Euclidean space. Based on this assumption, after summarizing topics with their topic-word distributions using the biterm topic model, we mapped these latent topics on networks to visualize relationships among the topics. Moreover, in the proposed approach, the change of relationships among topics can be traced using a trajectory plot generated with different levels of word richness. These results together provide a deeply mined and intuitive representation of relationships among topics related to a specific research area. The application of this proposed framework to the PubMed literature shows that our approach facilitates understanding of the topics constituting the COVID-19 knowledge.
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