<b><i>Background/Aims:</i></b> The aims of study were (1) to determine the cut-off values of parameters related to auditory perceptual assessment (visual analog scale [VAS]) and acoustic analysis (cepstral peak prominence [CPP], low-frequency/high-frequency [L/H] ratio, CPP SD, L/H ratio SD, acoustic voice quality index [AVQI], and cepstral spectral index of dysphonia [CSID]) for predicting voice problems within a Korean population, and (2) to verify the discriminative power of these cut-off values. <b><i>Methods:</i></b> 1,113 voice samples were analyzed in this study. Perceptual assessments (VAS) were performed by 5 speech-language pathologists. For the acoustic analysis, cepstral parameters, CSID, and AVQI were calculated. The cut-off values of parameters predicting voice problems were obtained using receiver operating characteristic (ROC) analysis. Additionally, the sensitivity, specificity, and area under the ROC curve (AUC) were measured. <b><i>Results:</i></b> High reliabilities were observed for the perceptual assessments. The cut-off values of parameters had a high sensitivity, specificity, and AUC. Of these, CSID was the parameter with the highest AUC values. <b><i>Conclusion:</i></b> Each parameter demonstrated a high discriminative power for classifying the presence or absence of voice problems. The results of this study could be used as an objective criterion for screening voice problems.
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