There is a growing interest in a hand-held ultrasound (US) system for a point-of-care diagnosis. In this paper, we present the hand-held smart US probe system, which includes analog and digital front-ends, mid-processor, and interface. In the analog front-end, 16 channels could be implemented using two eight-channel high-voltage pulsers and analog-to-digital converters (ADC). The following digital frontend was implemented using a single low-cost field programmable gate array chip (FPGA). The output data from the digital frontend are transferred to the commercial tablet PC via the USB 3.0 interface. The tablet PC performs the back-end processing and image display on a graphical user interface (GUI). The smart probe system developed can provide the real-time B-mode images up to 22 Hz of frame rate with 7 W of estimated maximum power consumption. The weight and dimension of the developed system are 73 g and 150 x 40 x 10 mm 3 in length, width, and height, respectively. To evaluate the performance of the proposed smart probe system, the phantom and in vivo experiments were conducted.
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