Abstrak
Latar Belakang: Karsinoma nasofaring (KNF) merupakan tumor yang unik karena etiologi dan distribusi
endemiknya. Di daerah endemik, etiologi KNF berkaitan dengan infeksi EBV. Infeksi EBV yang laten dan persisten
pada KNF menunjukkan pola laten tipe II yang ditandai dengan ekspresi EBNA-1, LMP-1, 2 dan EBER. LMP-1
merupakan gen laten EBV yang pertama ditemukan yang dapat mentransformasi galur sel, merubah fenotip sel,
menginduksi proliferasi dan mencegah apoptosis. Tujuan dari penelitian ini adalah mengetahui korelasi antara
ekspresi LMP-1 EBV dengan ekspresi p53 pada KNF. Cara: Empat puluh sembilan slaid HE dan blok parafin dari
KNF dianalisis dan dipulas secara imunohistokima dengan antibodi LMP-1 EBV dan p53. Korelasi antara ekspresi
LMP-1 dengan ekspresi p53 diuji dengan menggunakan uji Korelasi Pearson. Nilai p
This research was conducted to determine the factors that influence passenger loyalty in water transportation. The research approach used was a quantitative approach. The research data is primary data obtained through a survey technique. The data that has been collected was then analyzed by path analysis. The research results showed that: 1) service quality has a significant and positive effect on passenger satisfaction; 2) tarrif has a significant and positive effect on passenger satisfaction; 3) service quality has a significant and positive effect on passenger loyalty; 4) tarrif has a positive but not significant effect on passenger loyalty; 5) passenger satisfaction has a significant and positive effect on passenger loyalty; 6) service quality has a significant effect on passenger loyalty through passenger satisfaction, as well as; 7) tarrif has a positive and significant effect on passenger loyalty through passenger satisfaction at PT ASDP route Merak-Bakauheni.
Transportation is currently an important need besides clothing, food and shelter for every individual who is active, especially in metropolitan areas such as Jakarta, Bogor, Depok, Tangerang and Bekasi (Jabodetabek) which really require high mobility and demands punctuality is a challenge for transportation provider. KRL Commuter Line as a rail-based urban transportation service provider has the ability to answer the mobility needs of urban communities (Jabodetabek). However, this capability must be supported by qualified service quality, one of which is by implementing the 7P (Marketing Mix) marketing mix for KRL Commuter Line services. Lintas Manggarai-Cikarang is one of the KRL Commuter Line corridors that is included in the category of high passenger volume, so service to service users will be seen based on product factors, price, place, people, promotion, process and physical evidence and their relationship to customer satisfaction KRL Commuter Line crossing Manggarai-Cikarang. The results of the SEM-PLS analysis of product, price, promotion, people, and process factors have a significant value on customer satisfaction. However, the physical evidence and place factors do not have a significant effect on customer satisfaction. Furthermore, in future research, it is hoped that factors that do not have significance can be studied in more depth.
This research was conducted at small and medium businesses, namely PT Sumber Karya Indah, a company engaged in the manufacture of women’s bags. There are 10 activities in the process of producing women’s bags. This work system is analyzed using the Nordic Body Map (NBM) method, Rapid Whole Body Assessment (REBA), Work Risk Ergonomic Risk Assessment (WERA), and Biomechanics to see ergonomic risks. The results of the Nordic Body Map questionnaire after working compared to before showed that there were 6 parts of the body of workers that had the highest value, namely the upper neck, buttocks, waist, right hand, left thigh and right thigh. REBA and WERA analysis was carried out on 10 activities to find potentially problematic activities to work health and comfort. The results of the analysis showed that there were 2 activities with high categories of REBA analysis methods, gluing activities (with a score of 10) and sticking activities (with a score of 9). Based on the WERA analysis, the two activities also showed the 2 highest values in the medium category, each with a value of 36 and 34. While the Biomechanical Analysis of worker posture on the gluing activity obtained a thigh muscle pressure score of2440 N and the overall moment was 248 NM towards the left. For sticking activity, the score for the thigh muscle was 1974.2 N and the overall moment was 63.2 NM to the left. Based on the results of these four analyzes, it can be concluded that sticking and sticking activities require immediate ergonomic intervention to reduce occupational health risks.
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