The detecting and screening of explosives has become a global consideration in dealing with potential terrorism threats and the misuse of high explosives. Several detection techniques have been developed, but their disadvantages include the requirement of expensive equipment, complicated pre-treatment, and prolonged testing. So far, fluorescence-based sensors have been of great interest as they overcome the limitations of other techniques. BODIPY, which is a fluorophore, shows excellent fluorescence features, and it can be used as a sensor material for explosives detection. However, to date, BODIPY-based explosive sensors have not been explored in detail. This work reviews the recent developments on explosive sensors based on BODIPY and its analogs.
Nowadays, cancers and dementia, such as Alzheimer’s disease, are the most fatal causes of death. Many studies tried to understand the pathogenesis of those diseases clearly and develop a promising way to treat the diseases. Matrix metalloproteinases (MMPs) have been reported to be involved in the pathology of cancers and AD through tumor cell movement and amyloid degradation. Therefore, control of the levels and actions of MMPs, especially MMP-2 and MMP-9, is necessary to care for and/or cure cancer and AD. Various molecules have been examined for their potential application as regulators of MMPs expression and activity. Among the molecules, multiple metal complexes have shown advantages, including simple synthesis, less toxicity and specificity toward MMPs in cancer cells or in the brain. In this review, we summarize the recent studies and knowledge of metal complexes (e.g., Pt-, Ru-, Au-, Fe-, Cu-, Ni-, Zn-, and Sn-complexes) targeting MMPs and their potentials for treating and/or caring the most fatal human diseases, cancers and AD.
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