Alkyl 2-diazo-3-oxoalkanoates generate alkoxycarbonylketenes, which undergo an electrophilic ring expansion with aziridines to afford alkyl 2-(oxazolin-2-yl)alkanoates in good to excellent yields under microwave heating. The method is a convenient and clean reaction without any activators and catalysts and can be also applied in the synthesis of 2-(oxazolin-2-yl)alkanamides and 1-(oxazolin-2-yl)alkylphosphonates.

N-(2,2-Diphenylvinyl)-β-oxoamides are both the structural moiety of biologically active compounds and important synthetic intermediates. Structurally diverse N-(2,2-diphenylvinyl)-β-oxoamides are prepared efficiently from 2-diazo-1,3-dicarbonyl compounds and N-alkyl-2,2-diphenylaziridines via an electrophilic ring opening...

Various α,β-unsaturated (E)-alkenylphosphonamidates were prepared in excellent stereo- and regioselectivties via the electrophilic hydrophosphonylation of cyclic and acyclic imines with alkylphosphonochloridates in the presence of base. For unsaturated imines, only...

A novel and transition metal-free synthesis of benzo-δ-phosphonolactams from readily available ethyl arylmethylphos-phonochloridates and dibenzo[b,f][1,4]oxazepines was developed. The reaction includes tandem phosphonylation, deprotonation, intramolecular nucleophilic addition, and aromatization, affording various...

Alkyl 2-diazo-3-oxoalkanoates generate alkoxycarbonylketenes, which undergo an electrophilic ring expansion with aziridines to afford alkyl 2-(oxazolin-2-yl)alkanoates in good to excellent yields under microwave irradiation. The method can be also applied in the synthesis of 2-(oxazolin-2-yl)alkanamides and 1-(oxazolin-2-yl)alkylphosphonates.