GİRİŞZehirlenme vücuda zararlı olabilecek maddelerin ağız, solunum, damar yolu veya cilt gibi yollardan alınmasıdır (1) . Aşılar ve gelişmiş medikal tedavilerle infeksiyonların azalmasından sonra zehirlenmeler çocukluk çağında kazalar ve tümöral hastalıklarla beraber en önemli mortalite nedenlerini oluşturmak-tadır. Acil başvurularda trafik kazaları, düşme ve yanıklardan sonra zehirlenmeler çocukluk çağı kazaları
The incidence of latex sensitization in this study was lower than reported in the literature. Environmental factors such as the type and number of operations and geographical location may play a role in the development of latex sensitization.
Background/aim: Familial Mediterranean fever (FMF), the most common autoinflammatory disease in children, is characterized by recurrent febrile episodes. FMF is known to progress with chronic inflammation, particularly during attack periods. This study aimed to investigate the relationship of S100A12, an inflammatory marker, with attacks and inflammatory events in FMF patients. Materials and methods: The study included 57 patients diagnosed with FMF, 43 in an attack-free period and 14 in an attack period, and 31 healthy children as the control group. Only white blood cell (WBC) count, C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), and S100A12 level were analyzed in the control group. In addition, serum amyloid A (SAA), and fibrinogen levels were measured, and a mutation analysis was performed in the patient group. The results were compared among the attackfree period, acute attack FMF and control groups. Results: The mean age of patients and control group was 10 (2.5-18) and 9.5 (2.5-16) years, respectively. The CRP (p = 0.001), S100A12 (p = 0.003) and ESR (p= 0.001) values differed significantly between the FMF and control groups. S100A12 level (p = 0.027), WBC count (p = 0.003), CRP level (p = 0.0001), ESR (p = 0.004), and fibrinogen level (p = 0.001) differed significantly between the acute attack and attack-free period groups. SAA level (p = 0.05), ESR (p = 0.001), fibrinogen level (p = 0.001), WBC count (p = 0.001), and S100A12 level (p = 0.027) were higher in M694V homozygous FMF patients than in other FMF patients. 2 Conclusion: Patients with FMF had higher S100A12 levels than the control group, while the mean S100A12 concentration was higher in acute attack period patients than in attackfree period patients. S100A12 level might be an important indicator in the monitoring of chronic inflammation in patients with FMF.
Ge liş ta ri hi/Re cei ved: 04.03.2015 Ka bul ta ri hi/Ac cep ted: 15.05.2015 Giriş Salmonella enfeksiyonları dünyada yaygın olarak görülmektedir ve enterik ateş mortalitesi yüksek invaziv bir enfeksiyondur. Non-tifoidal Salmonella enfeksiyonları ise genellikle kendini sınırlayan gastroenteritler şeklinde karşımıza çıkmaktadırlar, ancak özellikle yaşlılık ve yenidoğan dönemi, malign hastalıklar, uzun süren kortikosteroid kullanımı, Human İmmundeficiency Virus (HIV) enfeksiyonu gibi immün sistemin baskılandığı durumlarda barsak duvarına penetre olan mikroorganizma ishal sonrası bakteriyemiye neden olmaktadır (1). Bakteriyemi ile beraber özellikle immun yetmezliği bulunan bireylerde karaciğer, dalak, beyin, kalp, kemik, deri ve kasta fokal abse odaklarına neden olabilmektedir (1-3). Salmonella türlerinin neden olduğu gluteal abse erişkinlerde görülmekle beraber bugüne kadar çocuklarda bildirilmemiştir (4-6). Burada daha önceden bilinen bir hastalığı bulunmayan 13 aylık bir kız çocuğunda ishal sonrası gelişen bir gluteal abse olgusu sunulmuştur. Olgu Sunumu On üç aylık kız hasta birkaç gün içinde giderek artan, sol gluteal bölgede daha fazla olmak üzere her iki gluteal bölgede kızarıklık, şişlik ve ateş yakınmalarıyla hastanemize getirildi. Hastanın on gün öncesine kadar yurtdışında yaşadığı ve orada iki ay süren ishal nedeniyle adını bilmedikleri antibiyotikleri oral yoldan ve gluteal bölgeden intramusküler olarak aldığı ve ishalinin düzeldiği öğrenildi. Aralarında akrabalık olmayan ABS tRACt Özet The non-typhoidal Salmonella infections normally cause self-limiting gastroenteritis; but invasive gastroenteritis may occur, especially in newborns, elderly and immunosuppresive patients. In addition to bacteriemia, it may cause severe infections such as meningitis, brain abscess, septic arthritis and soft tissue abscesses. Muscle abscesses caused by non-typhoid salmonella infections have been rarely reported in adults. Here, a 13-month-old girl who developed gluteal abscess due to Salmonella typhimirium after diarrhea is presented.
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