Our study has shown that a significant proportion of patients with BP are multimorbid and individually have a higher number of comorbidities compared to matched controls. Disease burden and multimorbidity may well impact the prognosis of patients with BP.

No abstract

Multidrug-resistant Salmonella is a well-recognised problem worldwide, especially in developing countries such as India, where non-typhoidal Salmonella infections and enteric fever are endemic. Antimicrobial resistance, particularly to fluoroquinolones, is common and leads to the frequent use of alternative agents, such as azithromycin. We herein describe the first reported case of azithromycin-resistant Salmonella gastroenteritis in a Singaporean patient.

No abstract

erythema (P = 0.016) and melanin (P = 0.031) did increase at the medial inferior orbital rim at 4-6 months. A proposed theory may be due to the deeper penetration through thinner tissue of the fractionated laser penetrating the reticular dermis and vessels and potentially the orbicularis oculi causing release of haemosiderin, which may not surface until 4-6 months.Melanin values were decreasing and no longer differed significantly from pre-operative values by 2-3 months. Erythema peaked at 2-3 months most notably at the lateral inferior orbital rim in both laser groups, but the degree of erythema did not significantly differ between laser groups (P > 0.05).Our data supports the well-known post treatment erythema and pigmentation described in the literature; patients will experience minimal and temporary, if any, increase in erythema or pigmentation. The findings in this study provide objective values in the melanin and erythema post-operatively which can aid in discussing expectations among patients receiving fractionated or traditional CO2 laser skin resurfacing as adjuvant facial rejuvenation therapy with transconjunctival lower lid blepharoplasty.