There is a need to introduce predictive models of nurses’ entrepreneurial intentions that can identify which variables will promote entrepreneurship among nurses. This study aimed to explore the factors influencing nurses’ entrepreneurial intentions. We performed a systematic review and developed prediction models using factors identified and validated in a meta-analysis. Moreover, we individually tested and compared three models based on: (1) the Theory of Planned Behavior, (2) a meta-analysis, and (3) a combination of the two. Data from 386 nurses were analyzed using SPSS 23.0 for Windows and AMOS 21.0. The squared multiple correlation statistics of Models 1, 2, and 3 were 54.3%, 35.8%, and 60.0%, respectively. Model 3 provided a better explanation of nurses’ entrepreneurial intentions. Attitude, subjective norm, perceived behavioral control, entrepreneurial orientation, and need for entrepreneurship education are the most important variables to strengthen the entrepreneurial intention of nurses. The results of this study can be used as a theoretical model to explain nurse entrepreneurship intentions. In addition, these findings offer a useful resource for constructing a start-up curriculum within nursing colleges that fosters prospective nursing entrepreneurs.
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