Background This study was designed to evaluate utility of transferring autologous adipose-derived mesenchymal stem cells with high regenerative capacity and adipose tissue derived-stromal vascular fraction, so-called 360 Vaginal Beautification technique, in labia majora augmentation and vaginal tightening operation. Methods A total of 97 female patients who underwent labia majora augmentation and vaginal tightening operation with 360 Vaginal Beautification technique were included. Post-discharge early (3rd and 7th postoperative day) and late (1 st and 3rd postoperative month) surgical complications were assessed , while the Female Genital Self-Image Scale (FGSIS) was applied before surgery and also during postoperative 6-12 months. Results All complications noted on postoperative 3rd day (ecchymosis of labia majus, ecchymosis of clitoral hood, tenderness in the pubic area and pain at the vaginal entrance points) regressed on postoperative 7th day with no infection, edema, lipoma or granuloma formation in any patient. Total mean FGSIS score was 17.7 ± 1.6 in the preoperative period, and increased significantly to 20.9 ± 1.4 and 22.2 ± 1.8 in the postoperative 6th month (p \ 0.001) and 12th month (p = 0.013), respectively.Conclusions The use of autologous fat, called 360 vaginal beautification, in the labia majora augmentation and vaginal tightening appears to be a safe technique due to use of autologous tissue transfer and to be associated with high satisfaction rate and an advantage of being more minimally invasive than surgical labia majora augmentation and vaginal tightening.
Back defects may occur after several factors such as cancer, trauma and pressure sores. These conditions are more frequent in adult group, whereas the etiological factor in newborn infants is usually meningomyelocele defects. The aim of this study is to define more reliable and easily applicable surgical technique for the closure of meningomy elocele defects. This study included a total of 15 infants who underwent operation with the diagnosis of meningomyelocele and were treated with a modified S flap at our clinic between January 2016 and January 2017. During surgery, two flaps with a random pattern planned from the healthy skin on the right and left side of the meningomyelocele defect were transposed to close the defect. The flap donor sites were primarily sutured by elevating the surrounding skin. The left-sided flap was designed with superior pedicle and the right one with inferior pedicle. Of the participants, 13 were females and two were males with a mean age of 3.2 (min-max: 1 to 16) days. The mean followup was 11.5 (min-max: 5 to 17) months. The mean defect size was 6.5x5 (min-max: 5x4 to 7x6) cm. The mean flap size was 6.5x2.9 cm for the flap planned from the left side and right side of the defect. Complication was observed only in one patients including partial necrosis. Our study results suggest that modified S flap is an easily applicable flap. The greatest advantage of this flap is the shortening of the operation time. However, the major disadvantage of this flap is the random pattern flap (absence of a known blood vessel)
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