A 4-year-old, neutered female, domestic shorthair cat admitted to the animal hospital for recurrent constipation presumed to be due to post-traumatic injuries, went into shock with signs including fever and ataxia followed by stupor. On the fifth day of hospitalization, the cat developed severe, diffuse oedema of the ventral abdomen with multifocal to coalescing erythematous areas and small vesicle formation. The results of bacteriological cultures of liver, spleen and kidney specimens led to the diagnosis of Acinetobacter baumannii sepsis. Histopathological findings of skin samples taken during necropsy showed an extensive epidermal and dermal necrosis with septic vasculitis and numerous intralesional gram-negative bacteria. Detection of the bla(OXA-51-like) gene specific for A. baumannii by PCR, performed retrospectively on samples of the deep layers of the skin, confirmed the presence of A. baumannii also in the cutaneous lesions. To our knowledge this is the first report of a necrotizing fasciitis with septic shock in a cat caused by A. baumannii.
Objectives-(1) To assess spinal cord blood flow (SCBF) during surgical treatment of disk extrusion in dogs and (2) to investigate associations between SCBF, clinical signs, presurgical MRI images, and 24-hour surgical outcome. Study Design-Cohort study. Animals-Chondrodystrophic dogs with thoracolumbar disk extrusion (n ¼ 12). Methods-Diagnosis was based on clinical signs and MRI findings, and confirmed at surgery. Regional SCBF was measured intraoperatively by laser-Doppler flowmetry before, immediately after surgical spinal cord decompression, and after 15 minutes of lavaging the lesion. Care was taken to ensure a standardized surgical procedure to minimize factors that could influence measurement readings.Results-A significant increase in intraoperative SCBF was found in all dogs (Wilcoxon's signedrank test; P ¼ .05) immediately after spinal cord decompression and after 15 minutes. Changes in SCBF were not associated with duration of clinical signs; initial or 24-hour neurologic status; or degree of spinal cord compression assessed by MRI. Conclusion-SCBF increases immediately after spinal cord decompression in dogs with disk herniation; however, increased SCBF was not associated with a diminished 24-hour neurologic status. Clinical Relevance-An increase in SCBF does not appear to be either associated with the degree of spinal cord compression or of a magnitude sufficient to outweigh the benefit of surgical decompression by resulting in clinically relevant changes in 24-hour outcome. r
| the VETERINARY RECORD SHORT COMMUNICATIONS catheter connected to a closed urine collection system. Routine blood work, including a complete blood count and serum chemistry profile, was unremarkable. Urinalysis revealed crystals suspected to be xanthine, and an inactive sediment. Plasma and 24-hour urine samples were submitted for xanthine and hypoxanthine measurements using HPLC and UV detection (Agilent 1000 series; Agilent Technologies), and 24-hour urine was submitted for uric acid measurements using a commercial enzymatic test (Roche Diagnostics) in an automatic analyser (Roche/ Hitachi Modular P800).Twenty-four-hour urine collection was subsequently performed in three unrelated male cats (control cats) that were presented for obstructive FLUTD not associated with crystalluria. The affected cat and the three controls were fed a regular adult moist maintenance diet before presentation and a diet for urinary tract disease (Feline Urinary Moist food; Royal Canin) during the time of sample collection. The plasma and urine xanthine and hypoxanthine levels were markedly higher, and urine uric acid levels were markedly lower, in the case than in the control cats ( Table 1). The urine xanthine:creatinine and hypoxanthine:creatinine ratios were higher, and the urine uric acid:creatinine ratio was lower, than in the three control cats (Table 1). These results are consistent with a lack of conversion of xanthine to uric acid, as would occur with a deficiency in xanthine oxidase, leading to xanthinuria.A perineal urethrostomy was performed and the cat made an uneventful recovery from the surgical procedure. It was treated with 0·01 mg/kg buprenorphine (Temegesic; Essex Chemie) intravenously every six hours for four days, 2·5 mg phenoxybenzamine (Phenoxybenzamin; Streuli) orally every 12 hours for three days, and 10 mg/kg amoxicillin and 2·5 mg/kg clavulanic acid (Clavaseptin; Vétoquinol) orally every 12 hours for 14 days.Five days after surgery, the cat was urinating without difficulty and was discharged from hospital in good general condition. A physical examin ation 11 months after surgery was unremarkable, and the cat continued to urinate without difficulty. It was still fed with regular commercial feline moist foods due to poor compliance with purine-restricted diets. A complete blood count was unremarkable and serum chemistry revealed mild azotaemia (urea 16·8 mmol/l, reference range 6·7 to 12·5 mmol/l; creatinine 185 µmol/l, reference range 53 to 141 µmol/l). Urinalysis revealed a specific gravity of 1·027, and an inactive sediment with very large numbers of yellow-brown spheroid crystals of varying size, resembling ammonium urates or amorphous urates (Fig 1). Urine bacterial culture revealed no growth. An abdominal ultrasound examination revealed small kidneys with mildly hypoechogenic cortices and suspected renal pelvic urolithiasis. Blood and urine spot samples were again analysed for purine concentrations. Xanthine and hypoxanthine were again markedly higher, and urine uric acid was again markedly lower, than...
A 10-year-old Domestic Shorthair cat was admitted for chronic ambulatory paraparesis and a spinal malformation. The clinical examination revealed paraparesis accentuated on the left side. Thoracolumbar radiographs revealed a spinal malformation with a narrowed intervertebral space between L1 and L2, and a dorsal fusion at the level of L2-L3 with a common dorsal process. Magnetic resonance imaging (MRI) revealed an intervertebral disk herniation with a ventral compression of the spinal cord at the level of L1/2. A standard vertebral lateral corpectomy with a foraminotomy was performed with a good outcome.
Abstract. A young, intact, male Bernese Mountain Dog was presented to the animal hospital for lameness and diffuse thickening of the soft tissue in the right hind limb. Magnetic resonance imaging revealed multiple, multilobular, space-occupying lesions within and between the muscles of the right femur. Biopsies taken from the lesions revealed an infiltrative mass composed mainly of collagen fibers and a low density of benignappearing fibroblasts. These findings were compatible with a diagnosis of a fibromatosis. Taking the age of onset into account, infantile fibromatosis was most likely. A deep fibromatosis, similar to that seen in adults, could not be excluded based on histology.
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