Background: Carcinoma of the gall bladder is the most common malignancy of the biliary tract. Ultrasonography guided Fine Needle Aspiration Cytology (FNAC) plays a crucial role in early detection of gall bladder (GB) lesions. Early diagnosis of GB lesions is a necessity in view of rising trend in GB carcinoma related mortality in India. The aim of this study is to determine the diagnostic accuracy of pre-operative ultrasonography guided FNAC in the diagnosis of GB masses. Methods: This was a retrospective observational study performed at a tertiary care university hospital over a period of one and a half years. A total of 47 patients with clinico-radiological suspicion of GB malignancy were subjected to USG guided FNA. 20 of these patients underwent diagnostic Trucut biopsy in addition to FNA. Results: Forty-one out of 47 patients analyzed were positive for malignancy with female preponderance; MF ratio of 0.6:1. There were 29 females (61.8%) and 18 males (38.2%) in the range of 34 to 85 years. Cytomorphology was inconclusive for malignancy in two patients and unsatisfactory in one case. Two were labeled as chronic cholecystitis and one as acute cholecystitis. Adenocarcinoma was the most common malignancy found in 36 patients (76.6%). Conclusion: USG guided FNAC is a rapid, safe and successful diagnostic procedure with high sensitivity for diagnosis of GB lesions. In the present scenario of increasing incidence of GB malignancy, FNAC has proved to be a useful first choice of investigation in the detection of GB lesions.
Background: The objective was to study adenomyosis and leiomyoma as the cause of abnormal uterine bleeding in hysterectomy specimens. Methods: This was a study carried out on 100 hysterectomy specimens, of subjects who presented to the department of Obstetrics and Gynaecology at Government Medical College, Patiala with the complaint of abnormal uterine bleeding. Data including age, parity, symptoms and clinical indication for hysterectomy was collected for the study and the histopathological findings were recorded. The specimens were well grossed and stained with hematoxylin and eosin and examined microscopically. Results: Women in the perimenopausal age (41-50 years) accounted for the highest number of cases (35, 44.30%) presenting with symptoms of AUB. In this age group leiomyoma was found to be the commonest cause of AUB (19, 54.28%). The most common symptom was heavy menstrual bleeding. Clinical, radiological and pathological evaluation correlated well with the diagnosis of leiomyoma but was of little help in diagnosing adenomyosis. Conclusion: Hence, adenomyosis still remains a clinical challenge and should be kept in mind by the clinician as well as the pathologist in women presenting with AUB.
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BSTRACT
Ectopic adrenal tissue is an uncommon entity in females. It is usually seen in male children, and the commonly involved sites are the kidney, retroperitoneum, spermatic cord, and paratesticular region. The ectopic adrenal gland in adults has been described in few studies only. Ectopic adrenal tissue was diagnosed as an incidental finding in histopathological examination of serous cystadenoma of the ovary. A 44-year-old female presented with a complaint of vague abdominal discomfort for the past few months. Ultrasound was suggestive of a left ovarian complex cystic lesion. The histopathological examination revealed serous cystadenoma with ectopic adrenal cell rest. Here, we present this case as it is a rare finding incidentally detected in a patient being operated on for a different pathology.
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