Background: Regional anesthesia is frequently used in obstetric, orthopedic, and urological procedures, commonly intrathecal and epidural local anesthetics are combined with opioids to prolong analgesia; however, these do not prolong the motor block time and can attenuate the response to surgical stress, in addition to being associated with side effects such as respiratory depression, urinary retention, pruritus, hemodynamic instability, nausea, and emesis. Objective: to investigate the effect of adding 75 mg ofmagnesium sulfate on the duration of sensory block and duration of motor block Patients and Methods: In a prospective randomized study, ASA I or II, 128 (64 control and 64 experimental groups) pregnant women (at term) who were candidate for cesarean section with spinal anesthesia, were recruited in this study. They were collected from "Baghdad Teaching Hospital" at the period from (September 2020 to Fab 2021).Each experimental woman received 12.5 mg (2.5 ml) of hyperbaric bupivacaine (0.5%) and 0.5 ml (75 mg) magnesium sulfate (15%), while controls received same does of hyperbaric bupivacaine and 0.5 ml of distilled water.
Results:The duration of analgesia (sensory blockade) and theduration of motor blockade manifested a statistically significant increase inexperimental as compared to their controls (control = 116.41 ± 12.47,experimental = 159.75 ± 10.56, control = 180.76 ± 11.83, experimental = 240 ±9.46 minutes respectively).
Conclusion:Significantly increased the duration ofpostoperative analgesia and prolonged the sensory and motor blockade withoutsignificant apparent maternal or fetal side effects.
Pain is the first general cause of consultation in most medical specialties, being also the most frequent cause of suffering and disability that seriously affects the quality of life of millions of people in the world. The aim is toevaluate the effectiveness of the use of ketorolac and metamizole in the treatment of postoperative acute adenotonsillectomypain in children.An interventional clinical trial study included 80children who were optionally subjected to adenotonsillectomy, within the age in the ranged from 5 to 12 years of age. Patients divided in two groups according to the analgesic regimen they received in the operating room, 40 children received Metamizole and 40 children received Ketorolac. In the Ketorolac group, 67.5% did not experience post-anesthetic recovery on the Ocher scale, and 32.5% had mild to moderate pain (1 to 6). In the Metamizole group, 27.5% of children reported no pain, and 72.5% rated their pain as mild to moderate. The degree of pain relief measured on the Oucher scale was higher in patients receiving Ketorolac (p <0.001). We concluded thatKetorolacis reducing postoperative pain significantly than metamizole in children undergoing to Adeno-tonsillectomy.
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