Hastalarda ikinci sıklıkta gastrointestinal tutulumun ortaya çıktığı (%69,2, n=63), bununla beraber sadece iki olguda invajinasyon geliştiği görüldü (%2,2). Eklem tutulumu sıklığı %64,8 (n=59) iken, olguların %16,4'ünde (n=15) renal tutulum ve bu olguların yalnızca %2,2'sinde (n=2) nefrotik düzeyde proteinüri saptandı. Olguların %8,8'inde (n=8) testiküler tutulum ve %1,1'inde (n=1) periferik sinir tutulumu gibi daha nadir bulgular geliştiği gözlendi. Çalışmamızda hastalığa bağlı nüks oranları düşük bulundu (%6,6, n=6). Sonuç: Çalışmamızda purpuradan sonraki en sık bulgunun gastrointestinal sistem tutulumu olması dikkat çekiciydi. Ciddi komplikasyonlar erken dönemde yine gastrointestinal tutuluma bağlı olarak görüldü. Bununla beraber hastalığa bağlı cerrahi komplikasyon ve nüks oranları düşüktü. Ortalama on aylık izlem sonunda prognozun iyi olduğu ve tüm olguların herhangi bir sekel bırakmadan iyileştiği gözlendi. Yine de HSP'li hastalarda özellikle renal tutulum varlığında uzun süreli izlemin önem taşıdığı sonucuna varıldı.Objective: Henoch-Schönlein purpura (HSP) is the most common childhood vasculitis, characterized by purpuric rash, arthritis, gastrointestinal system and renal involvement. In this study, our aim is to analyze the epidemiological, clinical and laboratory data of the children with HSP being followed-up at the Department of Pediatrics, Keçiören Training and Research Hospital. Method: HSP patients who were hospitalized between November 2006 and November 2011 and followed-up for at least six months were enrolled in the study. The patient records were analyzed retrospectively. Results: Ninety-one cases aged 2-17 years (48 girls, 43 boys) were enrolled in the study. Purpuric rash was present in all of the patients. Gastrointestinal involvement was detected in 69.2% (n=63) of the cases as the second common finding. However, invagination developed in only two cases (2.2%). Joint and renal involvement was present in 64.8% (n=59) and 16.4% (n=15) of the cases, respectively. Only 2.2% of the patients with renal involvement had nephrotic level of proteinuria (n=2). Rarer findings including testicular involvement and peripheric neuropathy were detected in 8.8% (n=8) and %1.1 (n=1) of the cases. Disease recurrence rate was low in our patient group (6.6%, n=6). Conclusion: It is remarkable that gastrointestinal involvement was the second most common finding in our study. Serious complications emerged in the early term, mainly due to gastrointestinal involvement. Meanwhile disease recurrence and surgical complication rates were relatively low and the course of HSP was benign in most of the cases. Nevertheless, it should be remembered that long-term follow-up patients (especially with renal involvement) is of great importance.Anahtar Kelimeler: Henoch-Schönlein purpurası, çocukluk yaş grubu, vaskülit.
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