Antibiotics used in food producing-animals may cause residual problems in food in terms of public health. This situation can lead to serious problems in terms of human health. Raw milk is one of the foods that are likely to contain antibiotics, even in trace amounts. This study aimed to determine the residue levels of commonly used antibiotics of raw goat's milk samples offered for sale in Ankara, belirlenmesi hedeflenmiştir. Bu amaçla; bir yıl içerisinde ve iki farklı dönemde olacak şekilde, 150 adet çiğ keçi sütü toplanmış ve HPLC yöntemi ile belirtilen antibiyotikler yönüyle analizleri gerçekleştirilmiştir. Enrofloksasin, sülfametoksazol, tilosin, penisilin G ve oksitetrasiklin için alıkonulma zamanları sırasıyla 7,9; 9,7; 11,5; 5,4; 7,3 dk. olarak; tespit limiti değerleri (LOD) sırayla 1,47; 0,8; 7,51; 2,69; 8,89 µg/L ve tayin limiti değerleri (LOQ) ise sırasıyla 4,47; 2,44; 22,78; 8,16; 26,96 µg/L olarak bulunmuştur. Yapılan analizler sonucunda da keçi sütü numunelerinde herhangi bir antibiyotik kalıntısı tespit edilememiştir. Keçilerin diğer süt veren hayvanlara göre hastalıklara direncinin daha yüksek olması, dolayısıyla da bu hayvanlarda antibiyotik kullanımının daha düşük olmasının bu sonuca ulaşılmasına sebep olduğu öngörülmektedir. Bu çalışma sonucunda elde edilen bulgular, halk sağlığı açısından değerlidir. Analizlerde antibiyotik kalıntısı bulunamaması önemlidir.
Medical stents are tubes made of a metal or plastic wire mesh. They are inserted into a hollow structure of a body part to keep an anatomic vessel or passageway open. Stents placed in the body can cause toxic effects by releasing metal ions into the body, and can also cause harmful effects on the body by creating corrosion products. In this study, the decomposition rate and release of corrosion products in artificial body fluid (PBS) of a stent sample with a nitinol structure produced for medical purposes were examined. If any metal decomposes in the body, it can endanger human life and can damage the body via heavy metal residues and toxic radical products that accumulate over long periods in the body. An in vitro degradation test was performed according to the standard 10993-13 and metal release values were found after short periods (one month) for nitinol. In the present study, the release values and possible toxic effects of nickel and titanium within the body with long-term intra-body use were examined. By calculating the mass loss caused by degradation, its relationship to heavy metal release inside the body and the possible side effects on human health of heavy metal residues were evaluated. Low metal ion release values of heavy metals resulting from degradation were determined by the ICP-OES device. Physical changes (diameter) in the surface of stent parts were also measured to compare and evaluate with the degradation rates.
Microalgae metabolites are used for the health, feed additives, cosmetic industries, food and biodiesel production. Phormidium species have an important position in medical studies because they contain essential components. In this study, carotenoid profile and content were analyzed using HPLC method. Antioxidant activities for Phormidium sp. were determinated using DPPH and FRAP assays. BHT and ASC were used as control samples in antioxidant assays. The saponified extract to seperate a range of carotenoids, verified a suitable separation as inferred from the retention factor (k) among 0.54 - 3.83 and the separation factor (α) values more than 1. Resolution peaks appointed to carotenoids (16) for Phormidium sp. was attained within the period time of 45 min. In the specie, main carotenoids identified were cis-Lutein, All-trans-lutein, All-transzeaxanthin, 13-or 13’-β-carotene, All-trans-β-carotene and 9-or 9’-cis-β-carotene. Auroxanthin and cisneoxanthin were identified as epoxy-containing compounds. It is also understood that considering the DPPH assay, the extract of Phormidium sp. (IC50:127.6 mg/L) exhibited clearly low radical scavenging activity compared to the standards ASC (IC50: 0.02 mg/L) and BHT (IC50: 0.19 mg/L). In the FRAP antioxidant experiment, the mean ASC and BHT equivalent amounts were determined as 828.6 and 124.6 mg/L, respectively. Quantitatively, Phormidium sp. was predominated by cis-Lutein as a major constituent, being 41.35 % (3.02 mg/g) in total carotenoids (Tc). The antioxidant capacity of Phormidium sp. that considering the DPPH and FRAP were compared to control standards were showed considerably low effects.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.