Growing number of excessively long on-chip wires in modern monolithic ICs is a byproduct of growing chip size. To address this problem instead of placing all system's components in one layer (i.e. in 2-D space) one can use a stack of single layer monolithic ICs (called here a 2.5-D integrated IC). To assess the potential benefits of such a 2.5-D integration schema this paper compares wire length distributions, obtained for 2-D and 2.5-D implementations of benchmark circuits. In the assessment two newly developed floorplanning and placement tools were used. Significant reductions in both total wirelength and worst-case wirelength was observed for the systems implemented as 2.5-D ICs.

As general-purpose processors have hit the power wall and chip fabrication cost escalates alarmingly, coarsegrained reconfigurable architectures (CGRAs) are attracting increasing interest from both academia and industry, because they offer the performance and energy efficiency of hardware with the flexibility of software. However, CGRAs are not yet mature in terms of programmability, productivity, and adaptability. This article reviews the architecture and design of CGRAs thoroughly for the purpose of exploiting their full potential. First, a novel multidimensional taxonomy is proposed. Second, major challenges and the corresponding state-of-the-art techniques are surveyed and analyzed. Finally, the future development is discussed. CCS Concepts: • Computer systems organization → Reconfigurable computing; • Hardware → Reconfigurable logic and FPGAs; • Theory of computation → Models of computation;

In this study, a fast and reliable method based on an ultra-high-pressure liquid chromatography coupled with photodiode-array detection (PDA) and a linear ion trap high-resolution mass spectrometer (LTQ-Orbitrap XL) has been developed for the identification of bioactive constituents in the whole plant of Sarcandra glabra and its related four preparations. By accurate mass measurements within 5 ppm error for each molecular ion and subsequent fragment ions in routine analysis, 50 compounds, including organic acids, caffeoyl derivatives, flavonoids, coumarins and terpenoids, were identified or tentatively characterized. Among them, 6,7,8-trihydroxycoumarin-O-rhamnopyranoside (17), (2R)-naringenin-6-C-B-D-glucopyranosyl-(6→1)-apiose (25) and (2S)-naringenin-6-C-B-D-glucopyranosyl-(6→1)-apiose (27) were tentatively identified as new compounds. Besides, 21 of these compounds were coexisting in four preparations of Sarcandra glabra. Fragmentation behaviors of the four major categories of compounds were also investigated. This established UPLC-PDA/ESI-MS(n) method was reliable and effective for the separation and identification of the major constituents and would be the basis for quality control of Sarcandra glabra and its related preparations.

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