ABSTRACT. Catalytically-driven electrochemical hydrogen evolution reaction (HER) of monolayered molybdenum sulfide (MoS 2 ) is usually highly supressed by the scarcity of edges and low electrical conductivity. Here, we show how the catalytic performance of MoS 2 monolayers can be improved dramatically by catalyst size reduction and surface sulphur (S)
Electrospinning is a simple and versatile encapsulation technology. Since electrospinning does not involve severe conditions of temperature or pressure or the use of harsh chemicals, it has great potential for effectively entrapping and delivering bioactive compounds. Recently, electrospinning has been used in the food industry to encapsulate bioactive compounds into different biopolymers (carbohydrates and proteins), protecting them from adverse environmental conditions, maintaining the health-promoting properties, and achieving their controlled release. Electrospinning opens a new horizon in food technology with possible commercialization in the near future. This review summarizes the principles and the types of electrospinning processes. The electrospinning of biopolymers and their application in encapsulating of bioactive compounds are highlighted. The existing scope, limitations, and future prospects of electrospinning bioactive compounds are also presented.
Contrast-enhanced imaging with coded harmonic angio may provide an alternative approach that has high diagnostic agreement with dynamic CT in assessing the therapeutic effect of radiofrequency ablation in hypervascular hepatocellular carcinomas, in spite of having limitations in identifying the safety margin.
Developing high-performance bifunctional electrocatalysts towards hydrogen evolution/oxidation reaction (HER/HOR) holds great significance for efficiently utilizing hydrogen energy. In this work, a unique class of Mo-modified Ru nanosheet assemblies (Mo-Ru NSAs)...
Phase pure titanium diboride (TiB2) powder of 100‐200 nm was synthesized from TiO2 and B2O3 using a molten‐salt‐assisted magnesiothermic reduction technique. The effects of salt type, Mg amount, reaction temperature, and TiO2 raw materials on the synthesis process were examined and the relevant reaction mechanisms discussed. Among the three chloride salts (NaCl, KCl, and MgCl2), MgCl2 showed the best accelerating‐effect. To synthesize phase pure TiB2, 20 mol% excessive Mg had to be used to compensate for the evaporation loss of Mg. Particle shape and size of raw material TiO2 showed little effect on the formation of TiB2 and its shape and size, suggesting that relatively cheaper and coarser TiO2 raw materials could be used for low‐temperature synthesis of TiB2 fine particles. The “dissolution‐precipitation” mechanism governed the overall molten salt synthesis process.
Curcumin, a naturally occurring polyphenolic compound present in turmeric (Curcuma longa), exerts antitumor effects in various types of malignancy. However, the precise mechanisms responsible for the effects of curcumin on retinoblastoma (RB) cells have not been fully explored. In the present study, the molecular mechanisms by which curcumin exerts its anticancer effects in RB Y79 cells were investigated. The results showed that curcumin reduced cell viability in Y79 cells. Curcumin induced G1 phase arrest through downregulating the expression of cyclin D3 and cyclin-dependent kinase (CDK)2/6 and upregulating the expression of CDK inhibitor proteins p21 and p27. Curcumin-induced apoptosis of Y79 cells occurred through the activation of caspases-9/-3. Moreover, flow cytometric analysis showed that curcumin induced mitochondrial membrane potential (∆Ψm) collapse in Y79 cells. We also found that curcumin induced the phosphorylation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK). JNK and p38 MAPK inhibitors significantly suppressed curcumin‑induced activation of caspases-9/-3 and inhibited the apoptosis of Y79 cells. Taken together, our results suggest that curcumin induced the apoptosis of Y79 cells through the activation of JNK and p38 MAPK pathways. These findings provide a novel treatment strategy for human RB.
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