Improving the rural living environment has become one of the hot issues in the study of rural revitalization in China. Based on 972 high-quality journal articles, in the database of China National Knowledge Infrastructure (CNKI), this paper provides a detailed bibliometric review of research on the improvement of the rural living environment in China, from 1992 to 2022. Based on a descriptive statistical analysis of the publication trends, authors, institutions, source journals, and high-frequency keywords of the sample literature, this paper uses cluster analysis and multidimensional scaling analysis to quantitatively analyze the main research fields, hot topics, and improvement directions. The results show, that the study of the improvement of the rural living environment presents a good trend. The main research include six aspects: rural sewage improvement, rural waste management, rural environment collaborative treatment, rural toilet improvement, new rural construction and management, and rural environmental green development. Among them, the research heat and abundance of research results of the first three, is higher than the latter three. To further deepen the research related to the rural living environment improvement in the future, issues such as rural toilet improvement, new rural construction and governance, and green development of rural environment, need more attention.
Oxovitisins are a unique group of anthocyanin derivatives with a non-oxonium nature and α-pyranone (lactone) D ring on the structure. In this study, oxovitisin A was synthesized through the micro-oxidative reaction of carboxypyranomalvidin-3-O-glucoside (vitisin A) with water, and its thermostability, pH, and SO2 color stability were studied compared with its two precursors, malvidin-3-O-glucoside (Mv3glc) and vitisin A, as well as methylpyrano-malvidin-3-O-glucoside (Me-py). Results showed that oxovitisin A exhibited the highest stabilities, which were inseparably related to its noncharged structure and the additional carbonyl group on the D ring. Moreover, the antiproliferative capacity of oxovitisin A was comparatively evaluated against two human gastrointestinal cancer cell lines. Interestingly, oxovitisin A presented the strongest antiproliferative ability on MKN-28 (IC50 = 538.42 ± 50.06 μM) and Caco-2 cells (IC50 = 434.85 ± 11.87 μM) compared with two other pyranoanthocyanins. Therefore, we conclude that oxovitisin A as a highly stable anthocyanin derivative still exhibits a satisfactory antiproliferative ability.
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