The solubilities of rutaecarpine in 12 organic solvents (dichloromethane, ethyl acetate, acetone, trichloromethane, ethoxyethane, butyl alcohol, isopropyl alcohol, ethyl alcohol, methyl alcohol, cyclohexane, hexane, and pentane) were measured over the temperature range of (283.2 to 323.2) K. The solubilities of rutaecarpine in selected organic solvents increase with the increasing of the temperature and were correlated by the modified Apelblat equation and a simplified thermodynamic equation. The dissolution enthalpy and entropy of rutaecarpine in these solvents were calculated using the van't Hoff equation. The results showed that the dissolution process was endothermic and entropy-driven.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.