Age-related changes in brain FDG uptake may be more accurately determined when applying the SPM method of voxel-based quantitative analysis on a template that best fits the characteristics of the analysed TEP images.
A combined visual and quantitative analysis improves the diagnostic accuracy to detect an MCI-like hypometabolic pattern in elderly patients with hypertension and subjective, isolated memory complaints.
BM normalization compares well with conventional SPM for the voxel-based quantitative analysis of the FDG-PET images from temporal epilepsy patients. Further studies in different population are needed to determine whether BM is truly an accurate alternative to SPM in this setting.
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