A sodalite-type porous metal-organic framework with polyoxometalate templates, H(3)[(Cu(4)Cl)(3)(BTC)(8)](2)[PW(12)O(40)]·(C(4)H(12)N)(6)·3H(2)O (NENU-11; BTC = 1,3,5-benzenetricarboxylate), was obtained by a hydrothermal reaction. As a reasonable candidate for eliminating nerve gas, NENU-11 displays good adsorption behavior for dimethyl methylphosphonate (15.5 molecules per formula unit). In virtue of the catalytic activity of polyoxometalate guests, this nerve gas mimic could be facilely decomposed by a hydrolysis reaction.

Key Points Question What factors are associated with self-reported psychological distress among school-aged children and adolescents during the COVID-19 pandemic? Findings In this cross-sectional study including 1 199 320 children and adolescents, the prevalence of self-reported psychological distress was 10.5%. Students who never wore a face mask were at higher risk for psychological distress compared with students who wore a face mask frequently, as were students who spent less than 0.5 hours exercising compared with students who spent more than 1 hour in exercising. Meaning These findings suggest that the prevalence of self-reported psychological distress among school-aged children and adolescents during the COVID-19 pandemic was relatively high.

Six FeIII centers are incorporated into the tungstophosphate anion [H2P2W12O48]12− upon reaction with FeCl3. The {P2W12Fe6} unit thus formed has been characterized in [H4P2W12Fe9O56(OAc)7]6− and [H56P8W48Fe28O248]28−. The latter is a supramolecular polyoxotungstate in which each of the four {P2W12Fe6} units is connected by three Fe‐O‐Fe bridges (see structure). Magnetic studies indicate strong antiferromagnetic coupling between the FeIII centers.

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Schizophrenia (SZ) is a neurodevelopmental disorder in which altered immune function typically plays an important role in mediating the effect of environmental insults and regulation of inflammation. The breast cancer suppressor protein associated protein (BRAP) is suggested to exert vital effects in neurodevelopment by modulating the mitogen-activated protein kinase cascade and inflammation signaling. To explore the possible role of BRAP in SZ, we conducted a two-stage study to examine the association of BRAP polymorphisms with SZ in the Han Chinese population. In stage one, we screened SNPs in BRAP from our GWAS data, which detected three associated SNPs, with rs3782886 being the most significant one (P  =  2.31E-6, OR  =  0.67). In stage two, we validated these three SNPs in an independently collected population including 1957 patients and 1509 controls, supporting the association of rs3782886 with SZ (P  =  1.43E-6, OR  =  0.73). Furthermore, cis-eQTL analysis indicates that rs3782886 genotypes are associated with mRNA levels of aldehyde dehydrogenase 2 family (ALDH2) (P  =  0.0039) and myosin regulatory light chain 2 (MYL2) (P < 1.0E-4). Our data suggest that the BRAP gene may confer vulnerability for SZ in Han Chinese population, adding further evidence for the involvement of developmental and/or neuroinflammatory cascades in the illness.

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1), has been synthesized and characterized by routine methods. In 1, the dimers constructed by two monosubstituted R-metatungstate [H 2 W 11 {Ce(H 2 O) 4 }O 39 ] 7-(simplified as {W 11 Ce} 7-) units are linked by Ce III and Ag I to form two-dimensional (2D) networks, and these networks are further connected by Ag I -Ag I ({Ag 2 } 2+ ) bonds to obtain a purely inorganic three-dimensional (3D) framework with two kinds of channels along the [1 0 0] and [0 1 0] directions. Furthermore, 1 exhibits reversible water sorption capability.