Conflicting reports exist in the literature with respect to the intracellular localization of catalase, D-amino acid oxidase and monoamine oxidase in liver. Studies performed by a number of different authors indicate that catalase is associated partly with cytoplasmic particles and partly with the supernatant fraction, the ratio of particulate to soluble activity depending on the species and sex of the aniimal and on the nature of the medium adopted for preparing the homogenate (Ludewig &

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