Three kinds of alloy carbides Fe6-xMoxC were precipitated during the transformation of austenite-to-bainite in molybdenum alloyed steel under the conditions of 12-T magnetic field and conventional treatment. The magnetic field induced Fe atom concentration in Fe6-xMoxC carbides was increased. The higher Fe atom content among three carbides (Fe2Mo4C, Fe3Mo3C and Fe4Mo2C) makes magnetic Gibbs free energy decreased remarkably. The measured aspect ratio of (Fe,Mo)6C carbides was ranged from 1∶1·16 to 1∶1·25, which was consistent with the calculated result according to the minimum energy principle. It was suggested that the high magnetic field had no visible influence on the morphology of (Fe,Mo)6C carbides.
Bone marrow-derived mesenchymal stem cells (BMSCs) can be recruited to tumor sites and integrate into the stroma of tumors. When co-cultured with BMSCs, otherwise weakly metastatic nasopharyngeal carcinoma cells (NPC) showed improved metastatic ability. BMSCs in the tumor environment displayed the characteristics of macrophages. Nitric oxide produced by BMSCs in tumor environment could translocate caldesmon to podosome in Ca2+/calmodulin manner and promoted metastatic ability of NPC cells through invadopodia formation, with which the NPC cells degrade the extracellular matrix. Thus, we concluded that the BMSCs promoted cell migration and invasion through nitric oxide-induced paracrine signals.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.