The DA-9701-induced improvement in GI transit and inhibition of plasma ACTH levels was mediated by the central CRF pathway.

The actions of methane on the intestine are influenced by the cholinergic pathway of the enteric nervous system. Our findings support the classification of methane as a gasotransmitter.

We introduce a notion of transitivity for approach uniformities and approach uniform convergence spaces, yielding reflective subconstructs ofAUnifandAUCS. Further, we investigate how these new categories are related touACHY,uACHY U , anduMET, and we show that these relationships are similar to those in the classical case.

Oral administration of YH12852 significantly accelerates and restores delayed upper and lower GI transit in a guinea pig model of POI. This drug may serve as a useful candidate for the treatment of postoperative ileus.