This analytical method is a validated measurement procedure for the determination and limit value monitoring of diethylene glycol, ethylene glycol and propylene glycol in workplace air. With this method simultaneously airborne glycols in the gaseous state as well as particles are collected. Sampling is performed by drawing a defined volume of air through the sampling system GGP‐Mini consisting of a glass fibre filter and a charcoal tube connected downstream using a suitable flow‐regulated pump. The flow rate is set to 0.33 L/min with a recommended air sample volume of 40 L. The collected glycols are desorbed with a mixture of dichloromethane/methanol containing 1‐hexanol as internal standard and then analysed by means of gas chromatography using FID. The quantitative evaluation is based on calibration functions obtained by means of multiple‐point calibrations. The limit of quantification (LOQ) for the individual glycols is 0.5 mg/m
3
based on an air sample volume of 40 L.
Joint Publication of the Analytical Subcommittee of the Chemistry Board of Experts of the Expert Committee Raw Materials and Chemical Industry of the German Social Accident Insurance and the working group “Air Analyses” of the Permanent Senate Commission of the Deutsche Forschungsgemeinschaft for the Investigation of Health Hazards of Chemical Compounds in the Work Area.
Quality control is crucially important in the arena of chemical analysis. Reference materials are essential for calibration and quality control processes, and for verification of the accuracy and reliability of the analytical results obtained. Owing to the complexity of their manufacture, reference materials for chemical agents occurring at workplaces are expensive and available only on a limited scale and for a small number of substances. Therefore, their cost-effective and fast production is an important aim. The Institute for Occupational Health and Safety (IFA) of the German Social Accident Insurance (DGUV) currently pursues different strategies for the production of reference materials. One strategy entails the use of a piezoelectric micro-dispensing system for non-contact spiking of extremely small quantities of substances with high reproducibility. The dispensing system is coupled to a semi-automated assembly unit for loading high numbers of samples. It is used for spiking phosphoric and sulphuric acid onto quartz fibre filters. Comparison of the results obtained on different days shows higher variability than results observed on the same day. However, after daily adjustment of the number of droplets to the current droplet volume, highly reproducible series with an adequate number of samples (>500) could be realized. The results of the internal quality control were verified in an interlaboratory comparison. Furthermore, storage stability was investigated systematically over a period of 2 years. The samples produced are suitable for use as reference materials for both inorganic acids.
Immer wieder sind Gerüche in Innenräumen Anlass für Beschwerden und lösen bei den Beschäftigten Besorgnis über eine Beeinträchtigung ihrer Gesundheit aus. Messungen von Stoffen in der Raumluft und die Bewertung anhand von Richt- oder Referenzwerten sind oft nicht zielführend. Die Konzentrationen sind häufig so niedrig, dass sie analytisch nicht quantifiziert werden können. Daher haben das Institut für Arbeitsschutz (IFA) und das Institut für Prävention und Arbeitsmedizin (IPA) der Deutschen Gesetzlichen Unfallversicherung ein Projekt zur Untersuchung der Wirkung und Bewertung von Gerüchen an Innenraumarbeitsplätzen durchgeführt. In Büroräumen ohne bekannte Innenraum- probleme, verifiziert durch Messungen von flüchtigen organischen Verbindungen (volatile organic compounds, VOC), Aldehyden und Kohlenstoffdioxid (CO2) sowie von Lufttemperatur und -feuchte, wurden durch Befragungen die Häufigkeit von Beschwerden über Raumklima, gesundheitliche Beschwerden und Angaben zur Geruchswahrnehmung und -belästigung ermittelt. Die Ergebnisse können nun als Vergleichswerte aus einer nicht belasteten, unauffälligen Referenzpopulation zur Objektivierung von Befindlichkeitsstörungen und Beschwerden über Geruchsbelästigungen herangezogen werden.
This analytical method is a validated measurement procedure for the determination and limit value monitoring of 1‐ethoxy‐2‐propanol, 1‐ethoxy‐2‐propyl acetate, 2‐(2‐methoxyethoxy)ethanol, 2‐(2‐ethoxyethoxy)ethanol and 2‐(2‐butoxyethoxy)ethanol in workplace air. With this method simultaneously airborne glycols in the gaseous state as well as particles are collected. Sampling is performed by drawing a defined volume of air through the sampling system GGP‐Mini consisting of a glass fibre filter and a charcoal tube connected downstream using a suitable flow‐regulated pump. The flow rate is set to 0.33 L/min with a recommended air sample volume of 40 L. The collected glycols are desorbed with a mixture of dichloromethane/methanol containing 1‐hexanol as internal standard and then analysed by means of gas chromatography using FID. The quantitative evaluation is based on calibration functions obtained by means of multiple‐point calibrations. The limit of quantification (LOQ) for the individual glycol esters or glycol ethers is 0.5 mg/m
3
based on an air sample volume of 40 L.
This analytical method is a validated measurement procedure for the determination and limit value monitoring of diethylene glycol, ethylene glycol and 1,2‐propylene glycol in workplace air. With this method simultaneously airborne glycols in the gaseous state as well as particles are collected. Sampling is performed by drawing a defined volume of air through the sampling system GGP‐Mini consisting of a glass fibre filter and a charcoal tube connected downstream using a suitable flow‐regulated pump. The flow rate is set to 0.33 L/min with a recommended air sample volume of 40 L. The collected glycols are desorbed with a mixture of dichloromethane/methanol containing 1‐hexanol as internal standard and then analysed by means of gas chromatography using FID. The quantitative evaluation is based on calibration functions obtained by means of multiple‐point calibrations. The limit of quantification (LOQ) for the individual glycols is 0.5 mg/m
3
based on an air sample volume of 40 L.
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