Statement of Problem: This review investigates laser benefits in second stage dental implant surgery as compared to conventional methods. Methods of Study: An electronic database search on PubMed, Cochrane library and LILACS for clinical studies in which laser was used for the second-stage implant surgery were selected and evaluated. Results: initial search yielded 136 studies, 15 were considered potentially relevant, out of which only three were finally selected. They studied the effect of laser on postoperative pain, the need for anesthesia and analgesia, hemostasis, time needed before impression and quality of it, duration of surgery and peri-implant soft tissue conditions. The results shows that the assessed studies are too limited in number beside exhibiting small sample sizes. They are clinically heterogeneous so that a solid conclusion cannot be reached. Conclusions: Researchers should be attracted to laser use to close a very obvious research gap. Randomized clinical trials are strongly recommended.
The ratio of stearic to oleic acids, i. e. the fatty acid saturation index, in red blood cell membranes was assayed in 60 patients with chronic hepatitis C virus infection before and after interferon-alpha therapy. Results were compared with 20 healthy controls. Hepatitis C virus titre was also assayed before and after interferon-alpha therapy. Within 2-5 months following interferon-alpha therapy, a significant inverse correlation was observed between saturation index and hepatitis C virus load. We conclude that hepatitis C virus infection enhances the degree of desaturation of 18-carbon fatty acids and that interferon-alpha is involved in their metabolism by increasing the degree of saturation and subsequent decrease in membrane fluidity.
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