Highlights Higher step count is inversely associated with the risk of premature death and cardiovascular events. As measured by accelerometers, 8959 steps/day (Q3) had a 40.36% lower risk of all-cause mortality than 4183 steps/day (Q1). As measured by accelerometers, 9500 steps/day (Q3) had a 35.05% lower risk of cardiovascular events than 3500 steps/day(Q1). These associations were in nonlinear dose–response patterns.

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