IntroductionIncidence of severe M. pneumoniae pneumonia (SMPP) reported in China has been increasing over the last decade. We aimed to evaluate the clinical features of pediatric SMPP with pulmonary complications, according to laboratory tests and chest radiographic resolution patterns.Material and MethodsWe retrospectively reviewed 93 SMPP patients between January 2016 and February 2019, and grouped them by pneumonia pattern: pulmonary complications (63 patients) and extensive lung lesions without pulmonary complications (30 patients).ResultsSMPP patients with pleural effusion (medium or large) and necrotizing pneumonia showed longer duration of fever, high serum value of lactate dehydrogenase (LDH), d‐dimer, and LDH to albumin ratio (LAR). LAR and d‐dimer were associated with moderate or massive pleural effusion, and d‐dimer was associated with lung necrosis. The average time of radiographic resolution in the pulmonary complication group was 12 weeks, while those with elevated d‐dimer were significantly more likely to have longer time for radiographic clearance.ConclusionWe conclude that M. pneumoniae pneumonia in patients with pleural effusion (medium or large) or lung necrosis was more severe than those without pulmonary complications. LAR and d‐dimer might be used as parameters to identify children susceptible to pleural effusion (medium or large) or lung necrosis, and longer time for radiographic clearance among pediatric patients of SMPP.
Background Incidence of severe M. pneumoniae pneumonia (SMPP) reported in China was increasing in the last decade. We aimed to evaluate clinical features in pediatric SMPP with pulmonary complications according to laboratory test and chest radiographic resolution patterns.Methods We retrospectively reviewed 93 SMPP patients between January 2016 and December 2018, and they were grouped by pneumonia pattern: pulmonary complication group (63 patients) and extensive lung lesion without pulmonary complication group (30 patients).Results SMPP patients of pleural effusion and necrotizing pneumonia showed longer fever duration, high serum value of lactic dehydrogenase (LDH), D-dimer and LDH to albumin ratio (LAR). LAR and D-dimer were associated with moderate and massive pleural effusion,and D-dimer was associated with lung necrosis. The average time of radiographic resolution in pulmonary complication group was 12 weeks, and those with elevated D-dimer were significantly more likely to have longer time to radiographic clearance.Conclusions M. pneumoniae pneumonia patients with pleural effusion or lung necrosis were more severe than those without pulmonary complication, LAR and D-dimer might be used as parameters to identify susceptible children of pleural effusion or lung necrosis and longer time to radiographic clearance among patients with SMPP.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.