Scheme 1. Illustration of the remote control cancer immunotherapy mediated by photothermal conjugated polymer nanoparticles (CPNs).

A conjugated polymer-based supramolecular system is designed for discrimination of virus and microbes. The supramolecular system is composed of cationic polythiophene derivative (PT) and barrel-shaped macrocyclic molecular cucurbit[7]uril (CB[7]). Because PT and PT/CB[7] complexes possess different interaction manners toward virus and microbes, the rapid and simple discrimination of virus and microbes was realized through polymer fluorescence intensity change assisting with standard linear discriminant analysis (LDA). The supramolecular strategy would expand the idea of designing biological probes and further promote the extensive application of conjugated polymer materials in biosensor field.

Constructing artificial hybrid biosystems, comprising of organisms and organic non‐biological functional material, will afford promising opportunities to achieve brand new or enhanced functions. In this work, a hybrid biosystem is designed and constructed by electrostatically recombining photoactive cationic poly(fluorene‐co‐phenylene) derivative (PFP) with a cyanobacterium (Synechococcus sp. PCC7942, Syne) for enhancing its photosynthesis and regulating exogenous redox state of protein. The light utility efficiency of Syne is significantly improved assisted by the excellent ultraviolet light‐harvesting ability of PFP, which accelerates electron‐transfer rate in non‐cyclic electron transport chain, and further augments the light‐dependent reaction in photosynthesis. As a result, O2, NADPH, and ATP production in the light‐dependent reaction are increased by 52.8%, 47.9%, and 27.2%, respectively. Moreover, the extracellular electron transfer property of Syne is able to realize electronic communication with external circumstances. Specifically, the electrons exported from Syne can reduce exogenous oxidized cytochrome c (Cyt c) and adsorbed PFP has the ability to regulate the reduction degree of Syne to Cyt c. This work reports an ideal design of a conjugated polymer‐based hybrid biosystem, providing a strategy to promote photosynthesis and regulate the redox state of protein.