In nowadays highly competitive and dynamic environment where employees' innovative work behaviour (IWB) has become critical source for business success, employees' quality of work lives is severely challenged by the global deregulated labour market. As an institutional effort to combat the challenges faced by labour world, the concept of decent work was proposed by International Labor Organization (ILO) in 1999, which is defined as work—and work‐related contexts—that provides adequate and fair income, social protection, security at workplace, opportunities for personal development and voice and participation in the decisions that affect their lives. This study examines whether realization of decent work promotes IWB. Based on a seven‐dimension construct of decent work, we propose that decent work promotes IWB through enhancing work engagement, with intrinsic motivation and job self‐efficacy partially mediating the positive effect of decent work on work engagement. By means of data with 517 supervisor–employee dyads, we test the hypotheses using structural equations modelling. Our results show good fitness of the hypothesized model, pass for the comparison of alternative models and testing of mediation effects and hence support all the hypotheses. Implications for theories and practices are discussed.
Aim: To investigate the effects of S-allylcysteine (SAC), a water-soluble garlic derivative, on human ovarian cancer cells in vitro. Methods: Human epithelial ovarian cancer cell line A2780 was tested. Cell proliferation was examined with CCK-8 and colony formation assays. Cell cycle was analyzed with flow cytometry. Cell apoptosis was studied using Hoechst 33258 staining and Annexin V/PI staining with flow cytometry. The migration and invasion of A2780 cells were examined with transwell and wound healing assays. The expression of relevant proteins was detected with Western blot assays. Results: SAC (1−100 mmol/L) inhibited the proliferation of A2780 cells in dose-and time-dependent manners (the IC 50 value was approximately 25 mmol/L at 48 h, and less than 6.25 mmol/L at 96 h). Furthermore, SAC dose-dependently inhibited the colony formation of A2780 cells. Treatment of A2780 cells with SAC resulted in G 1 /S phase arrest and induced apoptosis, accompanied by decreased expression of pro-caspase-3, Parp-1 and Bcl-2, and increased expression of active caspase-3 and Bax. SAC treatment significantly reduced the migration of A2780 cells, and markedly decreased the protein expression of Wnt5a, p-AKT and c-Jun, which were the key proteins involved in proliferation and metastasis. Conclusion: SAC suppresses proliferation and induces apoptosis in A2780 ovarian cancer cells in vitro.
The application of game elements of gamification in online shopping is attracting interest from researchers and practitioners. However, it remains unclear how gamification affects and improves consumer purchase intention on online shopping platforms, which still leaves a gap in our knowledge. To narrow this theoretical gap, a theoretical model has been built in this study. This model adopts cognitive evaluation theory to explain the impact of gamification elements on consumer purchase intention. Data was collected from 322 online shopping consumers who used a flash game to test their purchase intention after playing games. The results show that game rewards, absorption and autonomy of gamification positively enhance sense of enjoyment, and that it helps people meet their psychological needs, which ultimately affects the online purchase intention of consumers. This study is helpful in analyzing the factors involved in the successful introduction of gamification on online shopping platforms in more detail.
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