Objectives
Evidence-based healthcare contributes to the improvement of healthcare quality and informs healthcare decision-making. The provision of timely high-quality evidence is always required to fulfil the ever-changing needs and expectations of healthcare personnel. This study aimed to assess the needs and expectations of healthcare personnel regarding evidence-based healthcare in China.
Methods
We conducted a cross-sectional online survey from December 8, 2020 to January 15, 2021 involving 901 participants across China. Healthcare providers, policy makers, researchers and educators, and full-time postgraduate medical and nursing students working/living in China were eligible to participate. A self-developed questionnaire was used.
Results
Participants generally agreed that health-related research evidence was beneficial. Evidence-based resources, such as Cochrane resources, were only known or used by about half of the respondents due to difficulties related to availability and accessibility. Various types of resources, topics of evidence, and themes of workshops were of particular interest to most of the participants.
Conclusions
The dissemination and translation of evidence, provision of more support in evidence availability, offering evidence-based training, and determining the most in-demand research areas have been identified as priority areas of work which could fulfil the needs and expectations of healthcare personnel in China.
Background: To investigate the epidemiological characteristics and resistance changes of carbapenem-resistant organisms (CROs) under the COVID-19 outbreak to provide evidence for precise prevention and control measures against hospital-acquired infections during the pandemic. Methods: The distribution characteristics of CROs (i.e., carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii) were analyzed by collecting the results of the antibiotic susceptibility tests of diagnostic isolates from all patients. Using interrupted time series analysis, we applied Poisson and linear segmented regression models to evaluate the effects of COVID-19 on the numbers and drug resistance of CROs. We also conducted a stratified analysis using the Cochran–Mantel–Haenszel test. Results: The resistance rate of carbapenem-resistant Acinetobacter baumannii (CRAB) was 38.73% higher after the COVID-19 outbreak compared with before (p < 0.05). In addition, the long-term effect indicated that the prevalence of CRAB had a decreasing trend (p < 0.05). However, the overall resistance rate of Klebsiella pneumoniae did not significantly change after the COVID-19 outbreak. Stratified analysis revealed that the carbapenem-resistant Klebsiella pneumoniae (CRKP) rate increased in females (OR = 1.98, p < 0.05), those over 65 years old (OR = 1.49, p < 0.05), those with sputum samples (OR = 1.40, p < 0.05), and those in the neurology group (OR = 2.14, p < 0.05). Conclusion: The COVID-19 pandemic has affected the change in nosocomial infections and resistance rates in CROs, highlighting the need for hospitals to closely monitor CROs, especially in high-risk populations and clinical departments. It is possible that lower adherence to infection control in crowded wards and staffing shortages may have contributed to this trend during the COVID-19 pandemic, which warrants further research.
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