Emerging patterns (EPs) are itemsets whose supports change significantly from one dataset to another; they were recently proposed to capture multi-attribute contrasts between data classes, or trends over time. In this paper we propose a new classifier, CAEP, using the following main ideas based on EPs: (i) Each EP can sharply differentiate the class membership of a (possibly small) fraction of instances containing the EP, due to the big difference between its supports in the opposing classes; we define the differentiating power of the EP in terms of the supports and their ratio, on instances containing the EP. (ii) For each instance t, by aggregating the differentiating power of a fixed, automatically selected set of EPs, a score is obtained for each class. The scores for all classes are normalized and the largest score determines t's class. CAEP is suitable for many applications, even those with large volumes of high (e.g. 45) dimensional data; it does not depend on dimension reduction on data; and it is usually equally accurate on all classes even if their populations are unbalanced. Experiments show that CAEP has consistent good predictive accuracy, and it almost always outperforms C4.5 and CBA. By using efficient, border-based algorithms (developed elsewhere) to discover EPs, CAEP scales up on data volume and dimensionality. Observing that accuracy on the whole dataset is too coarse description of classifiers, we also used a more accurate measure, sensitivity and precision, to better characterize the performance of classifiers. CAEP is also very good under this measure.
Based on the recently proposed super valence bond model, in which superatoms can compose superatomic molecules by sharing valence pairs and nuclei for shell closure, the 23c-14e bi-icosahedral Au(23)((+9)) core of Au(38)(SR)(24) is proved to be a superatomic molecule. Molecular orbital analysis reveals that the Au(23)((+9)) core is an exact analogue of the F(2) molecule in electronic configuration. Chemical bonding analysis by the adaptive natural density partitioning method confirms the superatomic molecule bonding framework of Au(38)(SR)(24) in a straightforward manner.
Anomalies in online social networks can signify irregular, and often illegal behaviour. Detection of such anomalies has been used to identify malicious individuals, including spammers, sexual predators, and online fraudsters. In this paper we survey existing computational techniques for detecting anomalies in online social networks. We characterise anomalies as being either static or dynamic, and as being labelled or unlabelled, and survey methods for detecting these different types of anomalies. We suggest that the detection of anomalies in online social networks is composed of two sub-processes; the selection and calculation of network features, and the classification of observations from this feature space. In addition, this paper provides an overview of the types of problems that anomaly detection can address and identifies key areas for future research.
We described the derivation of four stable pluripotent rabbit embryonic stem cell (ESC) lines, one (RF) from blastocysts fertilized in vivo and cultured in vitro and three (RP01, RP02, and RP03) from parthenogenetic blastocysts. These ESC lines have been cultivated for extended periods (RF >1 year, RP01 >8 months, RP02 >8 months, and RP03 >6 months) in vitro while maintaining expression of pluripotent ESC markers and a normal XY or XX karyotype. The ESCs from all lines expressed alkaline phosphatase, transcription factor Oct-4, stage-specific embryonic antigens (SSEA-1, SSEA-3, and SSEA-4), and the tumor-related antigens (TRA-1-60 and TRA-1-81). Similar to human and mouse ESCs, rabbit ESCs expressed pluripotency (Oct-4, Nanog, SOX2, and UTF-1) and signaling pathway genes (fibroblast growth factor, WNT, and transforming growth factor pathway). Morphologically, rabbit ESCs resembled primate ESCs, whereas their proliferation characteristics were more like those seen in mouse ESCs. Rabbit ESCs were induced to differentiate into many cell types in vitro and formed teratomas with derivatives of the three major germ layers in vivo when injected into severe combined immunodeficient mice. Our results showed that pluripotent, stable ESC lines could be derived from fertilized and parthenote-derived rabbit embryos. STEM CELLS 2007;25:481-489
Do children need a longer time to shed SARS-CoV-2 in stool than adults? --The role of stool viral nucleic acid in children Abstract: SARS-CoV-2 can be shed in the stool of patients in the recovery phase. Children show a longer shedding time than adults. We analyzed the possible causes of this finding and recommend that a negative stool sample be included in a patient's discharge criteria.Introduction:
We describe the formation of amorphous selenium
(α-Se)/protein composites using Capsicum annuum L extract to reduce selenium ions
(SeO32−)
at room temperature. The reaction occurs rapidly and the process is simple and easy to handle. A
protein with a molecular weight of 30 kDa extracted from Capsicum annuum L not only reduces the
SeO32− ions
to Se0, but also controls the nucleation and growth of
Se0, and even participates
in the formation of α-Se/protein composites. The size and shell thickness of the
α-Se/protein composites increases with high Capsicum annuum L extract concentration, and
decreases with low reaction solution pH. The results suggest that this eco-friendly,
biogenic synthesis strategy could be widely used for preparing inorganic/organic
biocomposites. In addition, we also discuss the possible mechanism of the reduction of
SeO32−
ions by Capsicum annuum L extract.
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