Objective
To evaluate left atrial function in patients with triple‐vessel disease (TVD) without myocardial infarction by real‐time three‐dimensional echocardiography (RT‐3DE) and two‐dimensional speckle tracking imaging (2D‐STE).
Methods
Sixty patients with coronary artery disease (CAD) without myocardial infarction were classified into two groups in accordance with the coronary angiography results: group B (all triple‐vessel stenosis ≥ 50% and < 75%) and group C (all triple‐vessel stenosis ≥ 75%). Thirty healthy individuals were selected as group A. LA volume related parameters including left atrial maximum volume index (LAVImax), LA passive and active ejection fraction (LAPEF, LAAEF) and LA total ejection fraction (LATEF) were measured by RT‐3DE. The global peak atrial longitudinal systolic strain (LASRs), early and late diastolic LA strain (LASRe and LASRa) rates were measured by 2D‐STE.
Results
We found statistically significant differences between 2D‐STE and RT‐3DE related parameters of these three groups. Furthermore, in groups B and C, N‐terminal fragment brain natriuretic peptides (NT‐pro‐BNP) and left ventricular end‐diastolic pressure (LVEDP) were found to be significantly correlated with LASRs and LASRa. And NT‐pro‐BNP had a moderate correlation with LVEDP.
Conclusions
2D‐STE and RT‐3DE can assess the LA function in patients with TVD without myocardial infarction. And LA strain values may provide additional information for predicting increased LVEDP and NT‐pro‐BNP.
To evaluate carotid elasticity by using two-dimensional strain imaging (2DSI) in type 2 diabetes mellitus (T2DM) patients with nonalcoholic fatty liver disease (NAFLD). 98 patients with T2DM diagnosed in our hospital were selected. All the patients were without carotid plaque, which were proved by carotid ultrasonography. According to the fatty liver classification standard, patients were divided into three groups. There were 35 cases without NAFLD in group A, 33 cases with mild NAFLD in group B and 30 cases with moderate to severe NAFLD in group C. By using two-dimensional and M-mode ultrasound to measure the left carotid intima-media thickness (IMT), common carotid arterial systolic diameter (Ds) and diastolic diameter (Dd). The systolic peak velocity was measured by spectral Doppler ultrasound. The systolic global peak circumferential strain (CS), early and late systolic global circumferential strain rate (CSr) were measured by 2DSI. The stiffness parameters β1 and β2 were calculated by M-mode ultrasound and 2DSI separately. Among three groups, the Ds, Dd and systolic peak velocity showed no significant difference (all
P
> .05). In group C, IMT and β1 were obviously increased than those of groups A and B (all
P
< .05). Compared groups A and B, there were no significant difference in IMT and β1 (all
P
> .05). β2 was higher in groups B and C than those in group A, CS, CSr were lower in groups B and C than those in group A (both
P
> .05). The carotid elasticity of T2DM patients with NAFLD can be evaluated by 2DSI.
Purpose Using three-dimensional speckle tracking
echocardiography (3D-STE) to evaluate left ventricular (LV) function in
patients with triple vessel coronary artery disease(TVD) without
myocardial infarction. Methods Sixty patients with TVD without
myocardial infarction were divided into two groups according to the
results of coronary angiography. Group B (n=31):50%≤the stenosis rates
of all triple vessel coronary artery<75%; Group C (n=29):the stenosis
rates of all triple vessel coronary artery≥75%. Thirty healthy subjects
were recruited as the group A. We measured LV end-diastolic and
end-systolic volume (LVEDV, LVESV) and LV ejection fraction (LVEF) using
real-time three-dimensional echocardiography. The 3D-STE parameters of
LV included global longitudinal strain (GLS), global area strain (GAS),
global radial strain (GRS) and global circumferential strain (GCS).
Results In group C, LVEDV and LVESV were significantly
increased (all P<0.05), while LVEF, GLS, GRS, GCS and GAS were
significantly decreased compared with groups A and B (all
P<0.05). In groups A and B, there were no statistical
differences in LVEDV, LVESV and LVEF. However, GLS, GCS and GAS were
lower in group B than in group A (all P<0.05).
Conclusion Our study shows that 3D-STE can evaluate the LV
function in patients with triple vessel coronary artery disease without
myocardial infarction through multiple strain parameters.
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