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Background: To evaluate the effect of individualized education for patients with type 2 diabetes mellitus (T2DM). Methods: A total of 280 patients (158 males, mean age 63 ± 10 years) with T2DM were randomly divided into study and control group. Eysenck Personality questionnaire was used to assess the personality of the patients in the study group, which was provided us one-on-one counseling and individualized management plan. Group education was provided to the control group. Results: At the end of the study, the body mass index (21.5±2.5 vs 23.6±1.6 kg/m

Using data from a survey in Ankang district of Shaanxi province of China in 2011, this paper examines the protective effect of the NRSP on quality of life of the rural elderly, as well the moderating effect on association between family structure and quality of life. An instrumental variable approach is used. NRSP is shown to significantly improve the quality of life of rural elderly, and a robustness check shows that this effect is consistent across different sets of subgroups. Compared with the elderly who have at least one son, the quality of life of those who are childless or have only one child is significantly lower. The NRSP is more likely to significantly improve the quality of life of the one-child elderly. In addition, the associations between the NRSP and the different facets of quality of life of the elderly are significant except for the facet of sensory abilities.

One-only children have long been a research concern and previous studies have consistently found that one-only children posed academic advantages. However, we know very little about why one-only children scored higher in school examinations than their peers with siblings. Parental involvement might be the reason underlies this difference. This study compares the relationship between parental involvement and students’ academic achievement in families with only one child and families with more than one child in China. The results indicate that parents with only one child are more involved in their children’s learning compared with their counterparts with more than one child. The findings also suggest that parent-child communication and parent-child activities can positively predict one-only children’s academic performance, whereas parent-school contact negatively predicts non-only children’s academic performance. These findings highlight the complexity and importance of parental involvement in academic achievement and presents implications for future practice.

Aim This study aimed to explore the miR‐342‐3p expression in pre‐eclampsia (PE) placentas and confirm whether miR‐342‐3p exerts effects on proliferation and migration of HTR‐8/SVneo trophoblastic cells. Methods The PE placentas (n = 8) were taken from gravidas complicated by PE and delivered after 34 weeks. The chorionic plates and the basal plates were separately taken from the placenta disc near the position of umbilical cord insertion. RT‐qPCR was used to measure the expression of miR‐342‐3p in the chorionic plates and the basal plates. Cell invasion assay and MMT assay were used to assess the effects of miR‐342‐3p on proliferation and migration of HTR‐8/SVneo trophoblastic cells. Luciferase reporter assay and Western blotting were used to analyze the target of miR‐342‐3p and investigate the detailed mechanisms. Results The expression of miR‐342‐3p was upregulated in both basal plates and chorionic plates in patients with PE compared with healthy pregnant individuals. MiR‐342‐3p inhibitor suppressed the cell viability and invasion, and induced apoptosis in trophoblast cells. Furthermore, inhibitor of DNA binding (ID)‐4 (ID4) was a direct target of miR‐342‐3p, and knockdown of ID4 abrogated the regulation effect of miR‐342‐3p on cell viability, apoptosis and invasion. Conclusion Inhibition of miR‐342‐3p expression may suppress the occurrence of PE by targeting ID4 in vitro.