The present study investigates the effects of functional sensorial denervation, induced by administering capsaicin to hemiovariectomized adult female rats in each day of the estrus cycle, on ovulation and serum concentrations of estrogen and progesterone. The results indicate that the establishment of compensatory ovarian hypertrophy (COH) and compensatory ovulation (CO) depends on both the day of the estrous cycle when sensorial denervation was performed and on which ovary was extirpated. These results support the now accepted notion that the response of the ovaries to denervation is asymmetrical. The results seem to suggest that this asymmetric response is mediated by some specific neu-ral information that is registered in the ovary and sent to the CNS, that such information plays a role modulating the reactivity of the ovarian compartments to gonadotropins, and that the frequency of this signal varies along the estrus cycle.
This work presents a state of the art revision of the results from studies of asphalt aging found by researchers aimed at deepening understanding of this complex phenomenon. The background shows the evolution of asphalt aging, initially considering it as physical hardening and progressively recognizing it as a complex phenomenon having repercussions on asphalt durability and physical-chemical properties. This document aims to be a guide for understanding future investigations for developing new types and mixtures of asphalt having improved properties.
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