Higenamine is a β2‐agonist that has been included in the Prohibited List of the World Anti‐Doping Agency (WADA) since 2017. Meanwhile, it exists in plumula nelumbinis, a part of the lotus seed, and is commonly used as an ingredient in cuisines, herbal medicines, and nutritional supplements in China and other countries in East Asia. Therefore, an evaluation of the risk of an adverse analytical finding (AAF) of higenamine caused by plumula nelumbinis products is necessary in doping control. In this study, 14 volunteers took plumula nelumbinis capsules orally (0.34 g/caplet, 6 caplets/day, 7 days), and another 11 volunteers ingested higenamine tablets (three 5 mg tablets/day for 7 days). Urine samples were collected over a period of 14 days. All urine samples were subjected to quantitative dilute‐and‐shoot analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS). The analytical results showed that urinary higenamine concentrations exceeded the WADA reporting limit (10 ng/mL) during the drug period in most sample groups. The maximum higenamine concentration observed in the plumula nelumbinis capsule group was 500 ng/mL. Based on confidence interval theory, appropriate data were used to establish mathematical models. The models reflected that the higenamine concentration in urine can exceed the WADA reporting limit with a high probability after taking plumula nelumbinis capsules. In conclusion, oral administration of plumula nelumbinis capsules showed a high risk of an AAF due to higenamine.
Objective:To assess the mental health and experience of sport-related harassment and abuse of elite aquatic athletes and to analyze it in relation to gender and discipline.Design:Cross-sectional study using an anonymous survey.Setting:The FINA World Championships 2019.Participants:Registered athletes in the disciplines of swimming, diving, high diving, water polo, artistic swimming, and open water swimming.Interventions:Athletes completed an online or paper-based questionnaire.Main Outcome Measures:The main outcome measures included screening for depression (10-item version of the Center for Epidemiological Studies Depression Scale revised), eating disorders (Brief Eating Disorders in Athletes Questionnaire), the subjective need for psychotherapeutic support, and the experience of sport-related harassment and/or abuse.Results:A quarter (24.6%) of the 377 responding athletes were classified as depressed and 2.5% as having an eating disorder. More than 40% of the athletes stated that they wanted or needed psychotherapeutic support. Fifty-one athletes (14.9%) had experienced harassment/abuse in sport themselves, and 31 (9%) had witnessed it in another athlete. The experiences of harassment and abuse ranged from unwanted comments about body or appearance (40.2%) to rewards in sport for sexual favors (2.5%) and rape (0.3%). Athletes who had experienced harassment/abuse in sport themselves had higher average scores for depression and eating disorders, and more of them felt they needed psychotherapeutic support. Up to a third would not talk or report to anybody if they saw or experienced harassment/abuse, and less than 20% would talk to an official for help.Conclusion:Targeted initiatives are required to address mental health issues and harassment and abuse in sport in the FINA aquatic disciplines.
Objective: To assess the mental health and experience of sport-related harassment and abuse of athletes participating in the FINA World Championships 2019, and to analyse it in relation to gender and the aquatic disciplines. Design: Cross-sectional study using an anonymous questionnaire. Methods: During the Championships, registered athletes (swimmers, divers, high divers, water polo players, artistic swimmers, open-water swimmers) completed a survey including the main outcome measures of depression (CES-D-10), eating disorders (BEDA-Q), the subjective need for psychotherapeutic support, and the experience of harassment and/or abuse in their sports environment. Results: A quarter of the athletes (n=62, 24.6%) were classified as depressed and more than a third (n=111, 35.0%) as having an eating disorder. More than 40% of the athletes stated that they wanted or needed psychotherapeutic support for mental health problems. Fifty-one athletes (14.9%) had experienced harassment/abuse in sport themselves, and 31 (9%) had witnessed it in another athlete. The experiences of harassment and abuse ranged from unwanted comments about body or appearance (40.2%) to rewards in sport for sexual favours (2.5%) and rape (0.3%). Athletes who had experienced harassment/abuse in sport themselves had higher average scores for depression and eating disorders, and more of them needed psychotherapeutic support. Up to a third would not talk to anybody if they saw or experienced harassment/abuse, and less than 20% would talk to an official for help. Conclusion: Targeted initiatives are required to address the burden of mental health issues and harassment and abuse in sport in the FINA aquatic disciplines.
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