PurposeThe aim of this study is to investigate the trends in incidence and mortality, and explore any change in survival of penile cancer in the United States.MethodsWe obtained data from the Surveillance, Epidemiology, and End Results (SEER) database (2000–2018) utilizing the SEER Stat software. The joinpoint regression was used to analyze the secular trend of incidence and incidence-based mortality (IBM) stratified by age, race, and summary stage. The 5-year relative survival rate was also calculated.ResultThe age-adjusted rates of penile cancer patients were 0.38 (0.37–0.39) and 0.21 (0.2–0.21) for overall incidence and IBM, respectively. The 5-year relative survival rates were 67.7%, 66.99%, and 65.67% for the calendar periods of 2000–2004, 2005–2009, and 2010–2014, respectively. No significant changes in incidence by era were observed from 2000 to 2018 [annual percentage change (APC) = 0.5%, p = 0.064]. The IBM rate of penile cancer showed an initial significant increase from 2000 to 2002 (APC = 78.6%, 95% CI, −1.7–224.6) followed by a deceleration rate of 4.6% (95% CI, 3.9–5.3) during 2002 to 2018. No significant improvement in 5-year relative survival was observed. The trends by age, race, and summary stage in incidence and IBM were significantly different.ConclusionThis study, using population-level data from the SEER database, showed an increasing trend in IBM and no significant improvement in the 5-year relative survival rate. Meanwhile, the incidence of penile cancer exhibited a relatively stable trend during the study period. These results might be due to the lack of significant progress in the treatment and management of penile cancer patients in the United States in recent decades. More efforts, like increasing awareness among the general population and doctors, and centralized management, might be needed in the future to improve the survival of this rare disease.
In recent years, the development of unmanned driving technology requires continuous progress in environment perception technology. Aiming at the key research direction of infrared environment perception in unmanned driving technology, a lightweight real-time detection network model for infrared environment perception, IEPet, is proposed. The model backbone adds the BottleneckCSP module and the proposed DCAP attention module, which can significantly improve the detection ability and spatial position perception ability while maintaining light weight. At the same time, the model improves the detection accuracy by using a 3-scales detection head. Comparative experiments on the unmanned driving data set show that compared with the lightweight model YOLOv4-tiny, the model proposed in this paper has an increase in F1 Score by 1.48% and an average detection accuracy by 6.37% to reach 84.31%. And the model is lighter. It shows that the proposed IEPet model can better meet the excellent performance required for infrared environment perception.
In recent years, protecting important objects by simulating animal camouflage has been widely employed in many fields. Therefore, camouflaged object detection (COD) technology has emerged. COD is more difficult to achieve than traditional object detection techniques due to the high degree of fusion of objects camouflaged with the background. In this paper, we strive to more accurately and efficiently identify camouflaged objects. Inspired by the use of magnifiers to search for hidden objects in pictures, we propose a COD network that simulates the observation effect of a magnifier called the MAGnifier Network (MAGNet). Specifically, our MAGNet contains two parallel modules: the ergodic magnification module (EMM) and the attention focus module (AFM). The EMM is designed to mimic the process of a magnifier enlarging an image, and AFM is used to simulate the observation process in which human attention is highly focused on a particular region. The two sets of output camouflaged object maps were merged to simulate the observation of an object by a magnifier. In addition, a weighted key point area perception loss function, which is more applicable to COD, was designed based on two modules to give greater attention to the camouflaged object. Extensive experiments demonstrate that compared with 19 cutting-edge detection models, MAGNet can achieve the best comprehensive effect on eight evaluation metrics in the public COD dataset. Additionally, compared to other COD methods, MAGNet has lower computational complexity and faster segmentation. We also validated the model’s generalization ability on a military camouflaged object dataset constructed in-house. Finally, we experimentally explored some extended applications of COD.
Accurate tokamak plasma equilibrium solution in flux coordinates is crucial for many stability and transport studies. Different approaches for dealing with singularities in solving the nonlinear Grad–Shafranov (GS) equation in flux coordinates or also known as straight field line coordinates are proposed in this paper. The GS equation is solved by iterating the position of grids directly in flux coordinates, and hence, no additional errors are introduced due to mapping process for a convergent solution. The singularity at magnetic axis in flux coordinates is removed by using a novel coordinate transform technique. Different from other techniques previously developed, no assumption in boundary condition at magnetic axis is used. This is consistent with the fact that there is no physical boundary at the magnetic axis. A flux coordinate system with poloidal coordinate chosen as the geometric poloidal angle is proposed. It conquers the difficulty in no definition of poloidal coordinate in flux coordinates at separatrix because of the singularity at x-point(s) in a divertor configuration. It also simplifies the process for computing poloidal flux coordinate during the iteration for solving the nonlinear GS equation. Non-uniform grids can be applied in both radial and poloidal coordinates, which allows it to increase the spacial resolution near x-point(s) in a divertor configuration. Based on the model proposed in this paper, a new Flux coordinates based EQuilibrium solver (FEQ) in tokamaks is developed. The numerical solutions from this code agree well with both the analytic Solov’ev solution and the numerical one from the EFIT code for a divertor configuration in the EAST tokamak. This code can be applied for simulating different equilibria with prescribed shape, pressure and current profiles, i.e. including both limiter and divertor configurations, positive triangularity and negative triangularity, different β, arbitrary magnetic shear profile etc. It provides a powerful and convenient fixed-boundary inverse equilibrium solver including both magnetic axis and separatrix in the solution for tokamak researches.
In recent years, protecting important objects by simulating animal camouflage has been widely used in many fields. Therefore, the Camouflaged Object Detection (COD) technology has emerged. COD is more difficult than traditional target detection techniques because of the high degree of fusion of camouflaged objects with the background. In this paper, we strive to identify camouflaged objects more accurately. Inspired by humans using a magnifier to search for hidden objects in pictures, we propose a COD network that simulates the observation effect of a magnifier, termed Magnifier Network (MAGNet). Specifically, our MAGNet contains two parallel modules, i.e., Ergodic Magnify module (EMM) and Attention Focus module (AFM). The EMM is designed to mimic the magnifying process of a magnifier ergodicing an image, and the AFM is used to perform the observation process in which human attention is highly focused for focusing on a region. The two sets output camouflaged object maps are merged to achieve the effect of simulating the observation of the object by a magnifier. Extensive experiments demonstrate that compared with 14 cutting-edge detection models, the MAGNet can achieve the best comprehensive effect of 8 evaluation indicators on the public COD dataset, and the segmentation accuracy is significantly improved.
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