Study findings suggest that (1) processing speed contributes to the association between white matter microstructure and working memory in schizophrenia and (2) white matter impairment in schizophrenia is regional tract-specific, particularly in tracts normally supporting processing speed performance.
Topological insulators (TIs) are a new quantum phase of matter with topologically protected surface metallic states inside the insulating bulk states. Due to their unique single Dirac cone surface state, relatively low sheet resistance, and broadband optical operation, they have attracted enormous interests in both electronics and optics. Out of those above‐mentioned applications, electronic devices are seeking most attention until now. Here the experimental prototype for light processing device, TI‐coated microfiber (TCM), is demonstrated. Owing to the large Kerr coefficient of TI, TCM could operate as an effective optical Kerr switcher and broadband wavelength converter at the telecommunication band. This device could be well integrated with current high‐speed fiber optic communication networks and might well provide an approach for all‐optical signal processing through nonlinear processes. It is anticipated that few‐layer topological insulator might afford new opportunities for nonlinear photonic applications, especially in all‐optical routing, optical multiplication frequency, etc.
Familial clustering of schizophrenia (SCZ), bipolar disorder (BPD), and major depressive disorder (MDD) was systematically reported (Aukes et al, Genet Med 2012, 14, 338-341) and convergent evidence from genetics, symptomatology, and psychopharmacology imply that there are intrinsic connections between these three major psychiatric disorders, for example, any two or even three of these disorders could co-exist in some families. A total of 60, 838 single-nucleotide polymorphisms (SNPs) on chromosome 3 were genotyped by Affymetrix Genome-Wide Human SNP array 6.0 on 119 SCZ, 253 BPD (type-I), 177 MDD patients and 1,000 controls. The population of Shandong province was formed in 14 century and believed that it belongs to homogenous population. Associated SNPs were systematically revealed and outstanding susceptibility genes (CADPS, GRM7,KALRN, LSAMP, NLGN1, PRICKLE2, ROBO2) were identified. Unexpectedly, flanking genes for the associated SNPs distinctive for BPD and/or MDD were replicated in an enlarged cohort of 986 SCZ patients. The evidence from this chromosome 3 analysis supports the notion that both of bipolar and MDD might be subtypes of schizophrenia rather than independent disease entity.Also, a similar finding was detected on chromosome 5, 6, 7, and 8 (Chen et al. Am J Transl Res
In this study, we introduce a subwavelength periodic thin plate array into an acoustic metasurface and investigate the modulation effect on acoustic surface waves. Both anomalous sound refraction and reflection are observed in the metasurface, and an analytic expression is derived to clarify the underlying mechanism. We theoretically prove that flexible beam steering can be realized by phase gradient acoustic metasurfaces with deep subwavelength periodic modulation. This study potentially adds another degree of freedom to controlling sound transmission by using an acoustic metasurface.
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