Objective To investigate characteristics of peripapillary choroidal thickness (PCT) in Chinese patients with myopia without myopic maculopathy. Methods We retrospectively assessed 95 Chinese patients (95 eyes) with myopia without myopic maculopathy, who had visited the myopia clinic of Shandong Provincial Qianfoshan Hospital. Thirteen patients were excluded; the remaining 82 patients were divided into Groups 1 (spherical equivalent [SE], −0.5 to −6.0 D; axial length, 24–26 mm; n = 26), 2 (SE, −6.0 to −10.0 D; axial length, 26 to 28 mm; n = 34), and 3 (SE, ≥−10.0 D; axial length, ≥28 mm; n = 22). Enhanced depth imaging optical coherence tomography was used to measure PCT in inferior, superior, nasal, and temporal quadrants. Continuous variables were compared using one-way analysis of variance. Associations of PCT with SE and axial length were analyzed by Pearson correlation. Results PCT decreased with increasing SE and axial length in all quadrants. For each group, PCT was thickest in the temporal quadrant and thinnest in the inferior quadrant. PCT significantly differed between Groups 1 and 3 in superior, nasal, and temporal quadrants. Conclusions PCT decreased with increasing SE and axial length. PCT was thickest in the temporal quadrant and thinnest in the inferior quadrant in Chinese patients with myopia.

Systemic lupus erythematosus (SLE) is a chronic idiopathic autoimmune disease. SLE can involve almost any part of the eyes. However, bilateral angle-closure glaucoma due to lupus choroidopathy that is accompanied by polyserositis and nephropathy is rare. We report a 21-year-old woman whose clinical manifestations were diagnosed as bilateral angle-closure glaucoma caused by ciliochoroidal effusion. Subsequently, SLE and lupus nephritis were diagnosed on the basis of malar rash, photosensitivity, proteinuria, positive anti-Smith and anti-DNA antibodies, and a renal histopathological biopsy. After 1 month of treatment with steroids and immunosuppressive drugs, the patient’s intraocular pressure returned to normal, visual acuity improved, and lupus nephritis was effectively controlled. Bilateral secondary acute angle closure caused by SLE choroidal disease can be an ocular manifestation of SLE, and is usually accompanied by polyserositis and nephropathy. High-dose steroids and immunosuppressive therapy should be immediately and actively provided for this condition.

Aim To study the characteristics and relationship between peripapillary retinal nerve fiber layer (RNFL) and choroidal thickness in young people with myopia. Methods We retrospectively analyzed 92 cases (52 myopia, 40 emmetropia) regarding age, sex, refractive power, axial length (AL), and intraocular pressure. Peripapillary RNFL and choroidal thicknesses were measured by optical coherence tomography (OCT) in six sectors. Differences in thicknesses between the two groups were compared by single-factor analysis. Results RNFL was thickest in the inferotemporal sector (157.3 ± 19.66 µm) and thinnest in the nasal sector (58.78 ± 18.41 µm). Peripapillary choroid was thickest in the superonasal sector (176.37 ± 33.92 µm) and thinnest in the inferotemporal sector (131.79 ± 25.22 µm). The RNFL was thinner in the myopia group (99.04 ± 8.23 µm) vs the emmetropia group (103.25 ± 8.32 µm); significantly different in the superotemporal and inferonasal sectors. Peripapillary choroid thickness in the myopia group (148.65 ± 26.64 µm) was lower vs the emmetropia group (160.88 ± 29.06 µm); significantly different in the nasal, inferonasal, and inferotemporal sectors. RNFL thickness was negatively correlated with choroidal thickness in the nasal sector (r = −0.288). Conclusion Peripapillary RNFL and choroidal thicknesses showed regional distributions. RNFL was negatively correlated with PCT in the nasal sector, possibly related to eye axis growth and choroidal compensation.

No abstract