A highly sensitive amperometric sulfadiazine sensor based on coating multiwalled carbon nanotubes (MWCNTs) and N-octyl-pyridinium-hexafluorophosphate (OPPF(6)) ionic liquid composite on a glassy carbon (GC) electrode is described. The MWCNTs/OPPF(6) composite contributed new properties to electrochemical sensors by combining the advantages of both ionic liquids and MWCNTs. Compared with bare GC electrode, the electrocatalytic activity of MWCNTs/OPPF(6) generated a greatly improved electrochemical detection of sulfadiazine including low oxidation potential, high current responses, and good anti-fouling performance. The oxidation peak currents of sulfadiazine obtained on the MWCNTs/OPPF(6) coated GC electrode were proportional to the concentration of sulfadiazine within the range of 3.3-35.4 μM with a detection limit of 0.21 μM.
Abstract:A highly sensitive amperometric sulfadiazine sensor fabricated by electrochemical deposition of poly(cobalt tetraaminophthalocyanine) (poly(Co II TAPc)) on the surface of a multi-walled carbon nanotubes-Nafion (MWCNTs-Nafion) modified electrode is described. This electrode showed a very attractive performance by combining the advantages of Co II TAPc, MWCNTs, and Nafion. Compared with the bare glassy carbon electrode (GCE) and the MWCNTs-Nafion modified electrode, the electrocatalytic activity of poly(Co II TAPc)-coated MWCNTs-Nafion GCE generated greatly improved electrochemical detections toward sulfadiazine including low oxidation potential, high current responses, and good anti-fouling performance. The oxidation peak currents of sulfadiazine obtained on the new modified electrode increased linearly while increasing the concentration of sulfadiazine from 0.5 to 43.5 μmol/L with the detection limit of 0.17 μmol/L.
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