Opportunistic screening for osteoporosis can be performed using low‐dose computed tomography (LDCT) imaging obtained for other clinical indications. In this study we explored the CT‐derived bone mineral density (BMD) and prevalence of osteoporosis from thoracic LDCT in a large population cohort of Chinese men and women. A total of 69,095 adults (40,733 men and 28,362 women) received a thoracic LDCT scan for the purpose of lung cancer screening between 2018 and 2019, and data were obtained for analysis from the China Biobank Project, a prospective nationwide multicenter population study. Lumbar spine (L1–L2) trabecular volumetric bone mineral density (vBMD) was derived from these scans using quantitative computed tomography (QCT) software and the American College of Radiology QCT diagnostic criteria for osteoporosis were applied. Geographic regional differences in the prevalence of osteoporosis were assessed and the age‐standardized, population prevalence of osteoporosis in Chinese men and women was estimated from the 2010 China census. The prevalence of osteoporosis by QCT for the Chinese population aged >50 years was 29.0% for women and 13.5% for men, equating to 49.0 million and 22.8 million, respectively. In women, this rate is comparable to estimates from dual‐energy X‐ray absorptiometry (DXA), but in men, the prevalence is double. Prevalence varied geographically across China, with higher rates in the southwest and lower rates in the northeast. Trabecular vBMD decreased with age in both men and women. Women had higher peak trabecular vBMD (185.4 mg/cm3) than men (176.6 mg/cm3) at age 30 to 34 years, but older women had lower trabecular vBMD (62.4 mg/cm3) than men (92.1 mg/cm3) at age 80 years. We show that LDCT‐based opportunistic screening could identify large numbers of patients with low lumbar vBMD, and that future cohort studies are now required to evaluate the clinical utility of such screening in terms of fracture prevention and supporting national health economic analyses. © 2020 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR)..
Background: The outbreak of coronavirus disease 2019 (COVID-19) has presented serious threats to people's health and lives. Police officers are bravely fighting on the front lines of the epidemic. The main purpose of this study was to assess the prevalence and severity of psychological responses among police officers during the COVID-19 pandemic and find influencing factors in depression and anxiety. Methods: A cross-sectional online questionnaire was administered to police officers in Wuhu through WeChat, and data were collected between March 10 and 26, 2020. A total of 3,561 questionnaires were received, of which 3,517 were considered valid. The questionnaires included demographic information and a psychological survey. The depression scale of the Patient Health QuestionnaireQ9) and Generalized Anxiety Disorder scale were utilized to assess depression and anxiety, respectively. Results: The mean depression score of participants was 4.10±4.87 (0-27), and 12.17%had moderate-severe depression. The mean anxiety score of participants was 3.59±4.228 (0-21), and 8.79% had moderate-severe anxiety. Older and married police officers were at higher risk of anxiety. Those with a bachelor's degree or above, living near the city center, and taking sleeping pills were at greater risk of depression and anxiety. Auxiliary police had lower depression and anxiety scores. Depression scores were strongly correlated withanxiety scores (r=0.863, p<0.001). Conclusion: Our findings identify factors associated with higher levels of depression and anxiety that can be utilized to develop psychological interventions to improve the mental health of vulnerable populations during the COVID-19 pandemic.
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