Implantable Medical Devices (IMDs) have been widely used to treat chronic diseases such as cardiac arrhythmia and diabetes. Many IMDs are enabled with wireless communication capabilities and can communicate with an outside programmer/reader wirelessly. With the rapid growth of IMDs, IMD security becomes a critical issue since attacks on IMDs may directly harm the patient. Typical IMDs have very limited resource in terms of energy, computation and storage. In this research, we identify a new kind of attacks on IMDs -Resource Depletion (RD) attacks that could deplete IMD resources (e.g., battery power) quickly. The RD attacks could reduce the lifetime of an IMD from several years to a few weeks. The attacks can be easily launched but can not be defended by traditional cryptographic approaches. In this paper, we propose to utilize the patient's IMD access pattern and we design a novel Support Vector Machine (SVM) based scheme to address the RD attacks. Our SVM-based scheme is very effective in defending the RD attacks. Our experimental results show that the average detection rate of the SVM-based scheme is above 90%.

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Background Blood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin infusion systems. In recent years, deep learning techniques have been utilized for a more accurate BG level prediction system. However, continuous glucose monitoring (CGM) readings are susceptible to sensor errors. As a result, inaccurate CGM readings would affect BG prediction and make it unreliable, even if the most optimal machine learning model is used. Methods In this work, we propose a novel approach to predicting blood glucose level with a stacked Long short-term memory (LSTM) based deep recurrent neural network (RNN) model considering sensor fault. We use the Kalman smoothing technique for the correction of the inaccurate CGM readings due to sensor error. Results For the OhioT1DM (2018) dataset, containing eight weeks’ data from six different patients, we achieve an average RMSE of 6.45 and 17.24 mg/dl for 30 min and 60 min of prediction horizon (PH), respectively. Conclusions To the best of our knowledge, this is the leading average prediction accuracy for the ohioT1DM dataset. Different physiological information, e.g., Kalman smoothed CGM data, carbohydrates from the meal, bolus insulin, and cumulative step counts in a fixed time interval, are crafted to represent meaningful features used as input to the model. The goal of our approach is to lower the difference between the predicted CGM values and the fingerstick blood glucose readings—the ground truth. Our results indicate that the proposed approach is feasible for more reliable BG forecasting that might improve the performance of the artificial pancreas and insulin infusion system for T1D diabetes management.

Wireless insulin pumps have been widely deployed in hospitals and home healthcare systems. Most of them have limited security mechanisms embedded to protect them from malicious attacks. In this paper, two attacks against insulin pump systems via wireless links are investigated: a single acute overdose with a significant amount of medication and a chronic overdose with a small amount of extra medication over a long time period. They can be launched unobtrusively and may jeopardize patients' lives. It is very urgent to protect patients from these attacks. We propose a novel personalized patient infusion pattern based access control scheme (PIPAC) for wireless insulin pumps. This scheme employs supervised learning approaches to learn normal patient infusion patterns in terms of the dosage amount, rate, and time of infusion, which are automatically recorded in insulin pump logs. The generated regression models are used to dynamically configure a safe infusion range for abnormal infusion identification. This model includes two sub models for bolus (one type of insulin) abnormal dosage detection and basal abnormal rate detection. The proposed algorithms are evaluated with real insulin pump. The evaluation results demonstrate that our scheme is able to detect the two attacks with a very high success rate.