Our study reveals that for respiratory exhalation flows, the sizes of the largest droplets that would totally evaporate before falling 2 m away are between 60 and 100 microm, and these expelled large droplets are carried more than 6 m away by exhaled air at a velocity of 50 m/s (sneezing), more than 2 m away at a velocity of 10 m/s (coughing) and less than 1 m away at a velocity of 1 m/s (breathing). These findings are useful for developing effective engineering control methods for infectious diseases, and also for exploring the basic transmission mechanisms of the infectious diseases. There is a need to examine the air distribution systems in hospital wards for controlling both airborne and droplet-borne transmitted diseases.

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Size distributions of expiratory droplets expelled during coughing and speaking and the velocities of the expiration air jets of healthy volunteers were measured. Droplet size was measured using the interferometric Mie imaging (IMI) technique while the particle image velocimetry (PIV) technique was used for measuring air velocity. These techniques allowed measurements in close proximity to the mouth and avoided air sampling losses. The average expiration air velocity was 11.7 m/s for coughing and 3.9 m/s for speaking. Under the experimental setting, evaporation and condensation effects had negligible impact on the measured droplet size. The geometric mean diameter of droplets from coughing was 13.5 m and it was 16.0 m for speaking (counting 1-100). The estimated total number of droplets expelled ranged from 947 to 2085 per cough and 112-6720 for speaking. The estimated droplet concentrations for coughing ranged from 2.4 to 5.2 cm −3 per cough and 0.004-0.223 cm −3 for speaking.