Background: This paper aimed to analyze the output constancy of a medical linear accelerator using PTW QUICKCHECK webline and studied the sensitivity of the PTW QUICKCHECK webline . Materials and Methods: The paper statistically analyzed the output doses of 6 MV and 10 MV of photons and 6 MeV, 9 MeV, and 12 MeV of electrons from a medical linear accelerator measured before the daily treatment to assess the output stability of a medical linear accelerator. Some modifications were introduced by artificially altering the external irradiation conditions, and the percent variations from baseline values were noted. The gantry angle was changed and some deviations were established in the vertical, longitudinal and lateral directions to study the sensitivity of the PTW QUICKCHECK webline . The beam flatness, symmetry, radiation quality and output energy of 6 MV of photon energy were statistically analyzed. Results: Among the measurements, no parameters exceeded the tolerance of ±3%. QUICKCHECK webline was capable of detecting the variations in the central axis dose, flatness, symmetry and radiation quality under the testing conditions. Similar to the photon energy, electron energy measurements also confirmed that the detector was sensitive to a small variation in output introduced by the testing conditions. An important application of accelerator performance prediction in this study confirms the irreplaceable and important function of morning quality checks of a linear accelerator. Conclusions: The output dose measured before daily treatment using PTW QUICKCHECK webline to analyze the linear accelerator output constancy helps to decrease the system error, effectively reduces the errors of the accelerator system, and avoids serious mistakes.

These findings suggest that CCRT with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts, by enhancing apoptosis and suppressing angiogenesis. Based on these preclinical findings, we suggest that CCRT for the treatment of prostate cancer deserves further development.

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Conclusions: ESMO guidelines prioritizing LC management are implemented in all participating countries. High and intermediate level recommendations are implemented with minor modification regardless the phase of the pandemic. The differences among countries are not related to the phase of pandemic but mostly to the health system capacity and socioeconomic factors in each country.Legal entity responsible for the study: The authors.

The aim of this work was to develop a bioactive glass/hydroxylapatite/chitason composite material for bone repair. Different proportions of bioactive glass/hydroxylapatite/chitason mixture was make into scaffolds by the freeze-drying method. The microstructure and composition were observed and analysed. The third-generation rabbit mesenchymal stem cells were inoculated into the stent. The adhesion of the stent was detected, and the proliferation of cells on the stent was detected. The compatibility between the stent and cells was evaluated. The size and shapes of the prepared bioactive glass/hydroxylapatite/chitason stent were consistent with moulds. The stent has parous structure and no aggregation of bioactive glass was found. The rabbit mesenchymal stem adhered to the stent, and some cells extended and stretched out pseudopodia. Obvious proliferation of bone marrow stromal cells was found on the stent. The prepared bioactive glass/hydroxylapatite/chitason stents have good porosity, high mechanical strength, and good cell compatibility.