To facilitate precatalyst recovery and reuse, we have developed a fluorous, oxime-based palladacycle 1 and demonstrated that it is a very efficient and versatile precatalyst for a wide range of carbon-carbon bond formation reactions (Suzuki-Miyaura, Sonogashira, Stille, Heck, Glaser-type, and Kumada) in either aqueous or organic medium under microwave irradiation. Palladacycle 1 could be recovered through F-SPE in various coupling reactions with recovery ranging from 84 to 95% for the first cycle. Inductively coupled plasma optical emission spectrometry (ICP-OES) analyses of the Pd content in the crude product from each class of transformation indicated extremely low levels of leaching and the palladacycle could be reused four to five times without significant loss of activity.

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Water-binding foldamers have been rarely studied. By orienting both H-bond donors and acceptors toward their interior, two pyridine-derived crescent-shaped folding oligoamides were found to be capable of trapping both conventional and unconventional water dimer clusters in their cavity (∼2.5 Å radius). In the unconventional water dimer cluster, the two water molecules stay in contact via an unusual H-H interaction (2.25 Å) rather than the typical H-bond.

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C h emIn fo rm 2 0 1 2 , 4 3 , issu e 1 0 © 2 0 1 2 Wiley -VCH Verl ag G m b H & Co. K G a A , We i n he i m O xida tion O 0 212 DOI: 1 0.100 2/ch in.201 2100 32 O xidation R eac tions U sing P olyme r-Suppor ted 2-Be nz ene sulfonyl-3-(4-nitr ophenyl)oxaziridine. -( SUSANTO, W. ; L AM*, Y.; Te trahe dron 6 7 (201 1) 43, 8353 -8 359, http://dx .doi.org /10.10 16/j.te t.201 1.08. 058 ; Dep . C h em., Na tl. Univ . Singa pore, Singap ore 1 1754 3, Sing apore ; Eng.) -Nue sg en 10 -03 2

The thermally stable palladacycle promotes the Suzuki—Miyaura, Sonogashira, and Stille coupling reactions under microwave irradiation at high temperatures, thus significantly shortening the reaction time.