According to recent literature,
−
differential scanning calorimetry (DSC) is being proposed as an alternative technique
for the determination of solubility curves with the advantage of requiring a small quantity of sample (in the order of milligrams),
besides being a fast method: solubility data can be accessed in a few hours. In this work, DSC was applied for estimating the
solubility of organic molecules in aqueous and nonaqueous solutions. The method was carried out using four organic substances,
referred to here as substances A, B, C, and D, A and B being solubilized in water, C in a mixture of methanol−water 20 wt %, and
D in acetone.
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