The age at which patients with perfume allergy present for evaluation is similar to that of other contactants. Atopic individuals may be overrepresented in this group of patients. Face involvement is likely. White persons are more likely to react to fragrance mix, whereas in Asian patients benzyl salicylate was a more frequent allergen. Fragrance mix corrected with 85.6% of positive responses to fragrance ingredients. The addition of ylang ylang oil, narcissus oil, and sandalwood oil to fragrance mix would be expected to pick up 94.2% with positive responses to fragrance materials; adding balsam of Peru increases this to 96%.
SUMMARY
A waitress, aged 38 years, developed acute contact dermatitis of her hands after chopping salad plants. Patch tests to radish (Raphanus) and to allyl wothiocyanate and benzyl wothiocyanate produced positive reactions. Sinigrin, the thioglucoside of allyl isothiocyanate, was mixed in petrolatum with the enzyme myrosinase; the mixture produced a positive patch test reaction. Based on these preliminary findings, the immunochemical requisites of isothiocyanates (mustard oils) are discussed. A tabulation has been made of exposure risk to plants of the mustard family (Cruciferae) which yield these compounds; the plants include some commonly used culinary vegetables, salad plants, condiments and also horticultural plants.
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