A routine dissection of an 89-year-old female cadaver who had died of cardiopulmonary arrest revealed a unique case of hyperostosis frontalis interna (HFI). Multiple layers of spongy bone growth deep to the internal table were coupled with asymmetrical nodular growths. Slight superior sagittal sinus growth was also noted, which is atypical of this condition. Additionally, this cadaver represents one of the rarer and more severe forms of HFI, class C. A clear consensus on whether HFI presents a clinical risk has not been reached. We hope that this report on a unique manifestation of HFI will help clinicians in evaluating patients with this condition.
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