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Eleven du Pont operators participated in a special dimethylformamide metabolite (monomethylformamide, MMF) urine monitoring study to investigate a possible seasonal influence on urine metabolite concentrations. Variables considered included urine volume, MMF concentration, MMF mass, urine specific gravity, and ambient temperature. Statistical analysis revealed a 13% reduction in urine volume under hot weather conditions as a cause of increased MMF concentrations. A correction for this change in urine volume should be made subjectively.

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