PresbyPRK and presbyLASIK are comparable in efficacy, stability, predictability, and safety at 12 months postoperatively. PresbyPRK is a good alternative when presbyLASIK is contraindicated.
Objectives: To report the tolerability, safety, and efficacy of the lyophilized amniotic membrane (AM) Visio-AMTRIX placed under a bandage contact lens (BCL) in treating persistent epithelial defects (PEDs). Methods: This retrospective study included consecutive patients with PEDs treated with a lyophilized AM placed under the BCL. Patients with PEDs who did not respond to medical treatment were included. Patients with a follow-up time less than 3 months were excluded. Results: Eleven eyes of 11 patients (mean age, 61.6615.9 years) were included. Time from PED presentation to AM transplantation (AMT) was 27.764.9 days, with the mean PED area of 13.2611.3 mm 2 . Complete resolution was achieved in 8 of 11 eyes after a single AM graft. The epithelial defect persisted after the first AMT in three eyes (27.3%), and a second graft was necessary to achieve complete healing. The corneal epithelial defect healed in an average of 11.064.4 days after grafting. After PED resolution, the best-corrected visual acuity significantly improved from 0.6660.30 logMAR (20/91 Snellen) to 0.5860.24 logMAR (20/77 Snellen) (P¼0.036) compared with baseline. The AM resorbed within 2 weeks in all cases. No complication or recurrence was observed. Conclusions: A sutureless lyophilized AM under the BCL can resolve PEDs with a significant improvement in vision.
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